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Clinical Relevance of Genetic Factors in Pulmonary Diseases

  • Book
  • © 2018

Overview

Editors:
  1. Takeshi Kaneko

    1. Yokohama City University, Yokohama, Japan

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  • Describes the underlying genetic basis of common pulmonary diseases and discusses their pathogenesis and pathophysiology
  • Provide an essential basis for understanding different subtypes and phonotypes
  • Broadens the understanding of beginning and experienced researchers and clinicians engaged in the treatment of pulmonary diseases

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Table of contents (18 chapters)

  1. Front Matter

    Pages i-ix
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  3. Genetic Disorders in Pulmonary Disease

    1. Front Matter

      Pages 37-37
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    2. Bronchial Asthma: Is Asthma Inherited?

      • Nobuyuki Hizawa
      Pages 39-56

    3. COPD: Hereditary (A1-AT) and Non-hereditary—What Are the Roles of Genetic Factors in the Pathogenesis of COPD?

      • Nobuyuki Horita
      Pages 57-75

    4. Smoking Behavior and Cessation (Nicotine Addiction): Are Genetic Factors Involved in Smoking Behavior?

      • Tetsuya Kubota, Akihito Yokoyama
      Pages 77-91

    5. Cystic Fibrosis, Primary Ciliary Dyskinesia, and Diffuse Panbronchiolitis: Hereditary and Non-hereditary—What Are the Roles of Genetic Factors in the Pathogenesis of These Diseases?

      • Masaharu Shinkai
      Pages 93-106

    6. Pulmonary Fibrosis: Hereditary and Non-hereditary—What Are the Role of Genetic Factors in the Pathogenesis of Pulmonary Fibrosis?

      • Takafumi Suda
      Pages 107-133

    7. Other Diffuse Lung Diseases: Diffuse Cystic Lung Diseases (LAM, TSC, BHD), Sarcoidosis, Pulmonary Alveolar Proteinosis, and Pulmonary Alveolar Microlithiasis—What Are the Roles of Genetic Factors in the Pathogenesis of These Diseases?

      • Haruhiko Furusawa, Masahiro Masuo, Yoshihisa Nukui, Yasunari Miyazaki, Naohiko Inase
      Pages 135-160

    8. Pulmonary Vascular Diseases: Pulmonary Hypertension and HHT—What Are the Roles of Genetic Factors in the Pathogenesis of Pulmonary Vascular Diseases?

      • Toshihiko Sugiura, Koichiro Tatsumi
      Pages 161-167

    9. Mycobacterial Infection: TB and NTM—What Are the Roles of Genetic Factors in the Pathogenesis of Mycobacterial Infection?

      • Kazuko Yamamoto, Hiroshi Mukae
      Pages 169-191

    10. Pulmonary Malignancies (1): Lung Cancer—What Are the Roles of Genetic Factors in Lung Cancer Pathogenesis?

      • Naozumi Hashimoto, Mitsuo Sato, Yoshinori Hasegawa
      Pages 193-206

    11. Pulmonary Malignancies (2): Mesothelioma—What Are the Roles of Genetic Factors in the Pathogenesis of Mesothelioma?

      • Takashi Nakano, Eisuke Shibata, Kozo Kuribayashi, Yoshie Yoshikawa, Masaki Ohmuraya
      Pages 207-224

    12. Genetic Factors in Sleep Disorders: What Are the Roles of Genetic Factors in the Pathogenesis of Sleep Disorders?

      • Kiminobu Tanizawa, Kazuo Chin
      Pages 225-254

    13. Pharmacokinetics, Pharmacodynamics, and Toxicities: What Should We Know About Genetic Factors that Affect the Pharmacotherapy of Pulmonary Diseases?

      • Takashi Sato
      Pages 255-271

  4. Oncogenic Driver Mutation (Somatic Mutations) in Lung Cancer

    1. Front Matter

      Pages 273-273
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    2. EGFR: How Important Is EGFR Mutation Status in the Management of Lung Cancer?

      • Mizuki Haraguchi, Kazuhisa Takahashi
      Pages 275-293

    3. ALK and Others: How Important Are ALK and Other Mutations in the Management of Lung Cancer?

      • Hisatsugu Goto, Yasuhiko Nishioka
      Pages 295-315
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Keywords

About this book

This book describes the underlying genetic basis of common pulmonary diseases and discusses their pathogenesis and pathophysiology. These insights provide the basis for understanding different subtypes and phonotypes, and will promote better treatment strategies and individualized medicine. The book provides new and valuable information for the development of the areas of study, as well as practical guidelines for clinicians engaged in treating pulmonary diseases.

This volume of the Respiratory Disease Series – Diagnostic Tools and Disease Managements will broaden the understanding of beginning and experienced researchers and clinicians who treat pulmonary diseases. Moreover, residents and clinicians engaged in medical oncology will find it a valuable guide to support them in their day-to-day work.

Editors and Affiliations

  • Yokohama City University, Yokohama, Japan

    Takeshi Kaneko

About the editor

Hiroyuki Nakamura, Department of Respiratory Medicine, 
Tokyo Medical University, Ibaraki Medical Center, 
Ibaraki, 
Japan

Kazutetsu Aoshiba, 
Department of Respiratory Medicine, 
Tokyo Medical University, Ibaraki Medical Center, 
Ibaraki, 
Japan


Takeshi Kaneko, 

Department of Pulmonology, 
Yokohama City University Graduate School of Medicine, 
Yokohama, 
Japan



Bibliographic Information

  • Book Title: Clinical Relevance of Genetic Factors in Pulmonary Diseases

  • Editors: Takeshi Kaneko

  • Series Title: Respiratory Disease Series: Diagnostic Tools and Disease Managements

  • DOI: https://doi.org/10.1007/978-981-10-8144-6

  • Publisher: Springer Singapore

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer Nature Singapore Pte Ltd. 2018

  • Hardcover ISBN: 978-981-10-8143-9Published: 25 July 2018

  • Softcover ISBN: 978-981-13-4074-1Published: 26 December 2018

  • eBook ISBN: 978-981-10-8144-6Published: 12 July 2018

  • Series ISSN: 2509-5552

  • Series E-ISSN: 2509-5560

  • Edition Number: 1

  • Number of Pages: IX, 344

  • Number of Illustrations: 19 b/w illustrations, 36 illustrations in colour

  • Topics: Pneumology/Respiratory System, Human Genetics

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