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  • © 2016

Translational Biomedical Informatics

A Precision Medicine Perspective

  • Introduces methods and applications in translational biomedical informatics
  • Analyses cross-level data
  • Covers topics about standardization and privacy

Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 939)

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Table of contents (13 chapters)

  1. Front Matter

    Pages i-vi
  2. NGS for Sequence Variants

    • Shaolei Teng
    Pages 1-20
  3. RNA Bioinformatics for Precision Medicine

    • Jiajia Chen, Bairong Shen
    Pages 21-38
  4. Exploring Human Diseases and Biological Mechanisms by Protein Structure Prediction and Modeling

    • Juexin Wang, Joseph Luttrell IV, Ning Zhang, Saad Khan, NianQing Shi, Michael X. Wang et al.
    Pages 39-61
  5. Informatics for Metabolomics

    • Kanthida Kusonmano, Wanwipa Vongsangnak, Pramote Chumnanpuen
    Pages 91-115
  6. Metagenomics and Single-Cell Omics Data Analysis for Human Microbiome Research

    • Maozhen Han, Pengshuo Yang, Hao Zhou, Hongjun Li, Kang Ning
    Pages 117-137
  7. Medical Imaging Informatics

    • William Hsu, Suzie El-Saden, Ricky K. Taira
    Pages 167-224
  8. LIMS and Clinical Data Management

    • Yalan Chen, Yuxin Lin, Xuye Yuan, Bairong Shen
    Pages 225-239
  9. Biobanks and Their Clinical Application and Informatics Challenges

    • Lan Yang, Yalan Chen, Chunjiang Yu, Bairong Shen
    Pages 241-257
  10. XML, Ontologies, and Their Clinical Applications

    • Chunjiang Yu, Bairong Shen
    Pages 259-287
  11. Network-Based Biomedical Data Analysis

    • Yuxin Lin, Xuye Yuan, Bairong Shen
    Pages 309-332

About this book

This book introduces readers to essential methods and applications in translational biomedical informatics, which include biomedical big data, cloud computing and algorithms for understanding omics data, imaging data, electronic health records and public health data. The storage, retrieval, mining and knowledge discovery of biomedical big data will be among the key challenges for future translational research. The paradigm for precision medicine and healthcare needs to integratively analyze not only the data at the same level – e.g. different omics data at the molecular level – but also data from different levels – the molecular, cellular, tissue, clinical and public health level. This book discusses the following major aspects: the structure of cross-level data; clinical patient information and its shareability; and standardization and privacy. It offers a valuable guide for all biologists, biomedical informaticians and clinicians with an interest in Precision Medicine Informatics.


Editors and Affiliations

  • Center for Systems Biology, Soochow University, Jiangsu, China

    Bairong Shen

  • School of Informatics and Computing, Indiana University, Bloomington, USA

    Haixu Tang

  • Department of Biomedical Informatics, University of California San Diego, La Jolla, USA

    Xiaoqian Jiang

About the editors

Dr. Bairong Shen is Professor and Director of Center for Systems Biology, Soochow University and is also Director of Taicang Center for Translational Bioinformatics.

Dr. Haixu Tang is Professor at School of Informatics and Computing, Indiana University, Bloomington,USA

Dr. Xiaoqian Jiang is Assistant Professor at Department of Biomedical Informatics

University of California, San Diego, USA

Bibliographic Information

  • Book Title: Translational Biomedical Informatics

  • Book Subtitle: A Precision Medicine Perspective

  • Editors: Bairong Shen, Haixu Tang, Xiaoqian Jiang

  • Series Title: Advances in Experimental Medicine and Biology

  • DOI: https://doi.org/10.1007/978-981-10-1503-8

  • Publisher: Springer Singapore

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd. 2016

  • Hardcover ISBN: 978-981-10-1502-1Published: 15 November 2016

  • Softcover ISBN: 978-981-10-9369-2Published: 29 June 2018

  • eBook ISBN: 978-981-10-1503-8Published: 31 October 2016

  • Series ISSN: 0065-2598

  • Series E-ISSN: 2214-8019

  • Edition Number: 1

  • Number of Pages: VI, 332

  • Number of Illustrations: 49 b/w illustrations, 44 illustrations in colour

  • Topics: Bioinformatics, Molecular Medicine, Computational Biology/Bioinformatics

Buy it now

Buying options

eBook USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access