Overview
- Provides a state-of-the-art on recent developments and future directions in aquaporin research
- Provides a systematic and comprehensive overview into aquaporins
- Covers diverse aspects of aquaporin research
- Written by experts in this field
Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 969)
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Table of contents (18 chapters)
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Front Matter
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Back Matter
Keywords
About this book
This book provides a state-of-the-art report on our current understanding of aquaporins and the future direction of the field. Aquaporins (AQPs) are a group of water-channel proteins that are specifically permeable to water and other small molecules, such as glycerol and urea. To date thirteen water-channel proteins (AQP0 – AQP12) have been cloned and the mechanisms and physiological functions of water transport across biological membranes have long been the subject of interest. Recent advances in the molecular biology and physiology of water transport have yielded new insights into how and why water moves across cell membranes, and studies on aquaporin knockout mouse models suggest that aquaporins are involved in the development of some diseases and they may be useful targets of research into selective-inhibitor drugs. By focusing on the advances made over the last 20 years in the biophysics, genetics, protein structure, molecular biology, physiology, pathophysiology and pharmacology of aquaporins in mammalian cell membranes, this book provides novel insights into further mechanisms and the physiological significance of water and some small molecule transport in mammals in order to stimulate further research in new directions.
Editors and Affiliations
About the editor
Baoxue Yang is a professor and vice chairman of Department of Pharmacology at Peking University. He is also an adjunct professor at Jilin University and a visiting professor at Northeast Normal University. Prof. Yang has been studying urea transporter and aquaporins for nearly 20 years and published more than 70 original research articles in this field.
Bibliographic Information
Book Title: Aquaporins
Editors: Baoxue Yang
Series Title: Advances in Experimental Medicine and Biology
DOI: https://doi.org/10.1007/978-94-024-1057-0
Publisher: Springer Dordrecht
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature B.V. 2017
Softcover ISBN: 978-94-024-1478-3Published: 07 August 2018
eBook ISBN: 978-94-024-1057-0Published: 03 March 2017
Series ISSN: 0065-2598
Series E-ISSN: 2214-8019
Edition Number: 1
Number of Pages: XII, 278
Number of Illustrations: 10 b/w illustrations, 59 illustrations in colour
Topics: Pharmacology/Toxicology, Protein Science, Human Physiology, Membrane Biology