Advances in Experimental Medicine and Biology

Regulation of Cytokine Gene Expression in Immunity and Diseases

Editors: Ma, Xiaojing (Ed.)

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  • ​Provides cutting-edge research developments on the regulation of cytokine expression
  • Illustrates the regulation of cytokine expression in both healthy physiological conditions and in pathological situations
  • Covers all major cytokines with respect to the regulation of their gene expression and protein production
  • Written by experts in this field
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eBook $149.00
price for USA in USD (gross)
  • ISBN 978-94-024-0921-5
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $199.99
price for USA in USD
  • ISBN 978-94-024-0919-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $199.99
price for USA in USD
  • ISBN 978-94-024-1436-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

This book explores the major cytokines, such as IL-1 and IFN-γ, with respect to the regulation of their gene expression and protein production in specific immune cell types. It discusses both healthy physiological settings and in pathological situations in which the expression of some cytokines could be dysregulated, resulting in either immunodeficiency or exacerbated inflammatory sequelae in animal models as well as in human patients. Cytokines are important regulators of immune responses that require the highly coordinated participation and communication of multiple cell types. The expression of cytokines by various producer cell types is therefore carefully regulated in response to environmental cues at multiple levels: transcription, translation and posttranslational modification. Presenting cutting-edge advances in our understanding of the regulation of cytokine expression, this book is a valuable resource for anyone involved or interested in immune regulation.

 

About the authors

Dr. Xiaojing Ma is a professor from Department of Microbiology and Immunology, Weill Cornell Medical College, USA. He is also the chair professor and associate dean of School of Life Sciences and Biotechnology, Shanghai Jiao Tong University. He serves as the associate editor of The Journal of Immunology, and is in the editorial board of several international journals, such as The Journal of Experimental Medicine, Annual Review of Biomedical Science and Cellular and Molecular Immunology. His research focuses on molecular regulation of cytokine gene expression and their immunological activities in inflammatory diseases, and he has published more than 80 research articles on top journals in this field.

Table of contents (10 chapters)

Table of contents (10 chapters)

Buy this book

eBook $149.00
price for USA in USD (gross)
  • ISBN 978-94-024-0921-5
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $199.99
price for USA in USD
  • ISBN 978-94-024-0919-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $199.99
price for USA in USD
  • ISBN 978-94-024-1436-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Regulation of Cytokine Gene Expression in Immunity and Diseases
Editors
  • Xiaojing Ma
Series Title
Advances in Experimental Medicine and Biology
Series Volume
941
Copyright
2016
Publisher
Springer Netherlands
Copyright Holder
Springer Science+Business Media Dordrecht
eBook ISBN
978-94-024-0921-5
DOI
10.1007/978-94-024-0921-5
Hardcover ISBN
978-94-024-0919-2
Softcover ISBN
978-94-024-1436-3
Series ISSN
0065-2598
Edition Number
1
Number of Pages
VIII, 225
Number of Illustrations
1 b/w illustrations, 22 illustrations in colour
Topics