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Kinesins and Cancer

Editors: Kozielski, Frank (Ed.)

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  • Covers the entire, interdisciplinary field of kinesins and cancer through expert contributions
  • Offers a timely reference standard on the relevance of kinesins to cancer treatment
  • Contributes to potential initial validation of mitotic kinesins as targets for drug development in cancer chemotherapy
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eBook $119.00
price for USA in USD (gross)
  • ISBN 978-94-017-9732-0
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $179.99
price for USA in USD
  • ISBN 978-94-017-9731-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $159.99
price for USA in USD
  • Customers within the U.S. and Canada please contact Customer Service at +1-800-777-4643, Latin America please contact us at +1-212-460-1500 (24 hours a day, 7 days a week).
  • Due: November 18, 2016
  • ISBN 978-94-024-0365-7
  • Free shipping for individuals worldwide
About this book

This interdisciplinary volume collates research work on kinesins and cancer. Authors attempt to validate members of the kinesin superfamily as potential targets for drug development in cancer chemotherapy. The work begins by highlighting the importance of kinesins, summarising current knowledge and how they are shown to be crucial for mitosis. Chapters go on to explore how this family of proteins are emerging as a novel target for chemotherapeutic intervention and drug development.

Readers will learn how kinesins travel along microtubules to fulfill their many roles in intracellular transport or cell division. Several compounds that inhibit two mitotic kinesins (called Eg5 and CENP-E) have entered Phase I and II clinical trials and are explored in these chapters. Additional mitotic kinesins are currently being validated as drug targets, raising the possibility that the repertoire of kinesin-based drug targets may expand in the future.

The book is suitable as a reference standard for the field of kinesins and cancer. It will interest those in academia and pharmaceutical companies, and anyone with an interest in the medical relevance of these proteins, which cutting edge methodologies are now enabling us to understand in astonishing detail.

Table of contents (14 chapters)

Table of contents (14 chapters)

Buy this book

eBook $119.00
price for USA in USD (gross)
  • ISBN 978-94-017-9732-0
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $179.99
price for USA in USD
  • ISBN 978-94-017-9731-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $159.99
price for USA in USD
  • Customers within the U.S. and Canada please contact Customer Service at +1-800-777-4643, Latin America please contact us at +1-212-460-1500 (24 hours a day, 7 days a week).
  • Due: November 18, 2016
  • ISBN 978-94-024-0365-7
  • Free shipping for individuals worldwide
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Bibliographic Information

Bibliographic Information
Book Title
Kinesins and Cancer
Editors
  • Frank Kozielski
Copyright
2015
Publisher
Springer Netherlands
Copyright Holder
Springer Science+Business Media Dordrecht
eBook ISBN
978-94-017-9732-0
DOI
10.1007/978-94-017-9732-0
Hardcover ISBN
978-94-017-9731-3
Softcover ISBN
978-94-024-0365-7
Edition Number
1
Number of Pages
X, 271
Number of Illustrations
18 b/w illustrations, 32 illustrations in colour
Topics