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Hormonal Regulation of Mammary Tumors

Volume II: Peptide and Other Hormones

Authors: Leung, Benjamin

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  • ISBN 978-94-011-8045-0
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Softcover $109.00
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  • ISBN 978-94-011-8047-4
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About this book

The concept that hormones influence tumor growth originated in 1889 with the proposal of Albert Schinzinger who suggested that breast cancer is related to the ovaries. Several years later, Sir George Beatson observed that remission of disseminated breast cancer could be achieved in premenopausal patients by performing bilateral oophorectomy. As a result of the contri­ butions of Hedley Atkins, Charles Huggins and others, additive and ablative hormonal therapies have been widely used for the treatment of advanced breast cancers for several decades. Model systems to study the effects of hormones on growth and regression of breast tumors have been available for many years; however, the complexities of the hormonal environment have rendered in vivo studies difficult in man and experimental animals. Recently, the availability of long-term cultures of breast cancer cells has stimulated many investigators to use these cell lines to unravel the mechanisms of hormone action. Because of the extreme diversity and complexity of advances regarding the endocrinology of the breast and breast cancers, a multi-authored review was deemed necessary. It has been gratifying to receive contributions from many noted scholars. In Volume I of this monograph, the influence of steroid hormones and their antagonists upon normal and neoplastic tissues of the mammary gland are presented. In Volume II, the effects of peptide and other hormones are reviewed.

Table of contents (11 chapters)

  • Role of Prolactin or Placental Lactogen in Mammary Tumor Development in Experimental Animals

    Nagasawa, Hiroshi

    Pages 1-24

  • Prolactin and Prolactin Receptors in Tumor Development, Growth and Cellular Functions

    Kelly, Paul A. (et al.)

    Pages 25-62

  • Studies of Prolactin Receptors and the Possible Proliferative Role of Prolactin and Other Pituitary Factors in Human Breast Tumor Cells

    Shiu, Robert P. C.

    Pages 63-76

  • Mode of Action of Prolactin on Normal and Neoplastic Mammary Tissues

    Rillema, James A.

    Pages 77-87

  • Growth Factors for Hormone-Sensitive Tumor Cells

    Sirbasku, David A. (et al.)

    Pages 88-122

Buy this book

eBook $84.99
price for USA in USD (gross)
  • ISBN 978-94-011-8045-0
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $109.00
price for USA in USD
  • ISBN 978-94-011-8047-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Hormonal Regulation of Mammary Tumors
Book Subtitle
Volume II: Peptide and Other Hormones
Authors
Copyright
1982
Publisher
Springer Netherlands
Copyright Holder
Eden Press Inc.
eBook ISBN
978-94-011-8045-0
DOI
10.1007/978-94-011-8045-0
Softcover ISBN
978-94-011-8047-4
Edition Number
1
Number of Pages
XVI, 283
Topics