Ischaemic Heart Disease

1. Front Matter

   Pages i-xi

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2. Epidemiology of ischaemic heart disease

   • M. G. Marmot, J. I. Mann

   Pages 1-31

3. Pathology of ischaemic heart disease

   • M. J. Davies

   Pages 33-68

4. Coronary physiology and pathophysiology

   • J. I. E. Hoffman

   Pages 69-89

5. Mechanisms of angina pectoris

   • A. A. Quyyumi

   Pages 91-121

6. Haemodynamic and metabolic consequences of angina and myocardial infarction

   • P. A. Poole-Wilson

   Pages 123-148

7. Investigation and management of chronic stable angina

   • H. J. Dargie

   Pages 149-217

8. Investigation and management of unstable angina

   • P. A. Crean

   Pages 219-249

9. Investigation and management of acute myocardial infarction

   • C. D. J. Ilsley, M. B. Ablett

   Pages 251-286

10. Electrical consequences of myocardial infarction

    • E. Rowland

    Pages 287-296

11. Back Matter

    Pages 297-305

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This book attempts to focus on the most important clinical aspects of ischaemic heart disease. Clearly, in no way is it supposed to be a comprehensive review of the subject, but it does attempt to address the most important topics for everyday practising clinicians. The question of epidemiology is topical both in the lay and medical press and is, therefore, covered in some detail. It is the editor's opinion that proper understanding of the clinical manifestations of the disease and, therefore, subsequent investigation and treatment are based on a detailed understanding of the pathology and pathophysiology, and as a result these subjects have also been covered in detail. In the last decade there have been considerable advances in our understanding of the mechanisms of angina and also the haemodynamic and metabolic consequences of both angina and myocardial infarction. Again, if appropriate investigations and treatment are to be undertaken, they can only be done with the proper knowledge of the disease being investigated. Finally, the investigation and management of the various mani­ festations of ischaemic heart disease have been addressed. In the last ten years there has been an explosion in the drugs available for the treatment of ischaemic heart disease and how they should be used has become much more sophisticated. The place of coronary artery surgery has now been rationalized and angioplasty provides an important adjunct to treatment.

• angina pectoris
• heart
• heart disease
• myocardial infarction
• physiology

• National Heart Hospital, London, UK

  Kim M. Fox

Policies and ethics