Medical Science Symposia Series

Multiple Risk Factors in Cardiovascular Disease

Strategies of Prevention of Coronary Heart Disease, Cardiac Failure, and Stroke

Editors: Gotto Jr., A.M., Lenfant, C., Paoletti, R., Catapano, A.L., Jackson, A.S. (Eds.)

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About this book

This volume is a collection of the most significant contributions to the 4th International Symposium on MULTIPLE RISK FACTORS IN CARDIOVASCULAR DISEASE: STRATEGIES OF PREVENTION OF CORONARY HEART DISEASE, CARDIAC F AlLURE, AND STROKE held in Washington, D. C. in April 1997. The meeting focused on the risk factors for cardiovascular disease and their interactions. The need for this symposium is based on the epidemiological, clinical, and biological evidence that individuals from industrialized countries often possess two or more risk factors which synergistically increase the global risk profile. This has become more evident in recent years with the increase in life expectancy of populations in the industrialized countries. The evidence that a combination of risk factors confers a very high risk of developing cardiovascular diseases, is of pivotal interest in the process of detection of patients who will benefit the most from pharmacological treatment. Many recent epidemiological data identifying the intrinsic and environmental factors contributing to the development of atherosclerosis are discussed. These results, in parallel with basic and clinical research, underline atherosclerosis as a complex and multifactorial process involving the influences of lipids, including lipoprotein subfractions, blood pressure rheologic forces, carbohydrate tolerance, and thrombogenic factors, including fibrinogen, tissue factor, PAl-I, and homocysteine. Furthennore, the risk associated with anyone of these risk factors varies widely depending on the level of the associated atherogenic risk factors. Hyper­ cholesterolemia and hypertriglyceridemia, for instance, are more common than would be expected by chance among hypertensive patients.

Table of contents (40 chapters)

Table of contents (40 chapters)
  • New Insights into the Role of HDL in the Development of Cardiovascular Disease

    Pages 1-7

    Brewer, H. Bryan, Jr.

  • Mechanisms of the Hypolipidemic Action of Fibrates

    Pages 9-17

    Auwerx, Johan (et al.)

  • Lipid Lowering Drugs and the Arterial Wall

    Pages 19-24

    Paoletti, R. (et al.)

  • Perspectives on Lipid-Lowering Therapy: Past and Present

    Pages 25-33

    Gotto, Antonio M., Jr.

  • Role of the Fibrinolytic and the Coagulation System in the Formation and Disorders of Blood Vessels

    Pages 35-44

    Carmeliet, Peter (et al.)

Buy this book

eBook $59.99
price for USA in USD (gross)
  • ISBN 978-94-011-5022-4
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $79.99
price for USA in USD
  • ISBN 978-94-010-6108-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Multiple Risk Factors in Cardiovascular Disease
Book Subtitle
Strategies of Prevention of Coronary Heart Disease, Cardiac Failure, and Stroke
Editors
  • Antonio M. Gotto Jr.
  • Claude Lenfant
  • Rodolfo Paoletti
  • Alberico L. Catapano
  • Ann S. Jackson
Series Title
Medical Science Symposia Series
Series Volume
12
Copyright
1998
Publisher
Springer Netherlands
Copyright Holder
Springer Science+Business Media Dordrecht
eBook ISBN
978-94-011-5022-4
DOI
10.1007/978-94-011-5022-4
Softcover ISBN
978-94-010-6108-7
Series ISSN
0928-9550
Edition Number
1
Number of Pages
XVII, 371
Topics