Applications of Supercritical Fluids in Industrial Analysis

1. Front Matter

   Pages i-xiv

   PDF

2. Properties of supercritical fluids

   • S. M. Hitchen, J. R. Dean

   Pages 1-11

3. Instrumentation for supercritical fluid chromatography

   • T. Greibrokk

   Pages 12-45

4. Instrumentation for supercritical fluid extraction

   • J. R. Dean, M. Kane

   Pages 46-73

5. Supercritical fluid chromatography and extraction of pharmaceuticals

   • I. D. Wilson, P. Davis, R. J. Ruane

   Pages 74-103

6. Applications of supercritical fluids in polymer analysis

   • D. E. Knowles, T. K. Hoge

   Pages 104-129

7. Applications of supercritical fluids in food science

   • J. R. Dean

   Pages 130-158

8. Supercritical fluid extraction in environmental analysis

   • V. Janda, K. Bartle, A. A. Clifford

   Pages 159-187

9. Future developments in analytical supercritical fluid technology: some ideas from recent research

   • T. P. Lynch

   Pages 188-218

10. Back Matter

    Pages 219-224

    PDF

The continued search for rapid, efficient and cost-effective means of analytical measurement has introduced supercritical fluids into the field of analytical chemistry. Two areas are common: supercritical fluid chroma­ tography and supercritical fluid extraction. Both seek to exploit the unique properties of a gas at temperatures and pressures above the critical point. The most common supercritical fluid is carbon dioxide, employed because of its low critical temperature (31 °C), inertness, purity, non-toxicity and cheapness. Alternative supercritical fluids are also used and often in conjunction with modifiers. The combined gas-like mass transfer and liquid-like solvating characteristics have been used for improved chroma­ tographic separation and faster sample preparation. Supercritical fluid chromatography (SFC) is complementary to gas chro­ matography ( GC) and high performance liquid chromatography (HPLC), providing higher efficiency than HPLC, together with the ability to analyse thermally labile and high molecular weight analytes. Both packed and open tubular columns can be employed, providing the capability to analyse a wide range of sample types. In addition, flame ionization detection can be used, thus providing 'universal' detection.

• Atom
• Chromat
• Lipid
• chromatography
• extraction
• pharmaceutical chemistry
• polymer
• supercritical fluid

...well organized and edited and can be recommended to those who want to apply SFC/SFE in their work. - Trends in Analytical Chemistry.; In conclusion, the book makes a useful contribution in transfering supercritical fluid methods from a basic study area to an application that solves real problems. - Chemistry in Britain

• Department of Chemical and Life Sciences, University of Northumbria at Newcastle, UK

  John R. Dean

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