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The role of interleukin-2 in the treatment of cancer patients

  • Book
  • © 1993

Overview

Editors:
  1. John Wagstaff

    1. Department of Oncology, Free University Hospital, Amsterdam, The Netherlands

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Table of contents (10 chapters)

  1. Front Matter

    Pages i-x
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  2. Introduction

    • John Wagstaff
    Pages 1-5

  3. Interleukin-2 as single agent

    • Lorenz M. Jost, Rolf A. Stahel
    Pages 7-28

  4. Interleukin-2 and lymphokine activated killer (LAK) cells

    • Sylvie Negrier, Thierry O. Philip
    Pages 29-43

  5. Interleukin-2 toxicity: mechanisms and management

    • Johanna W. Baars
    Pages 45-69

  6. Interleukin-2 biology and immunology

    • Giorgio Parmiani, Carlo Gambacorti-Passerini
    Pages 71-83

  7. Interleukin-2 and tumour eradication by cytotoxic T lymphocytes

    • Cornelis J. M. Melief, W. Martin Kast
    Pages 85-94

  8. Combination treatment with Interleukin-2 and chemotherapeutic agents

    • Albert Von Rohr, Nick Thatcher
    Pages 95-121

  9. Interleukin-2, lymphocytes and monoclonal antibodies

    • Reinder L. H. Bolhuis, Gerrit Stoter
    Pages 123-140

  10. Interleukin-2 and other cytokines

    • Jens Atzpodien, Axel Schomburg, Hartmut Kirchner, Hubert Poliwoda
    Pages 141-167

  11. Future prospects for Interleukin-2 therapy

    • Christopher R. Franks, Peter A. Palmer
    Pages 169-185

  12. Back Matter

    Pages 187-191
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Keywords

About this book

Recombinant human interleukin-2 became available for clinical use in the mid 1980s. Recent years have seen an enormous amount of clinical research with this cytokine and interleukin-2 has now been registered for use in a number of European countries for the treatment of metastatic renal cell carcinoma. This book is designed to provide the clinical oncologist wishing to use interleukin-2 with a basic background concerning the biology of the agent, a discussion concerning practical aspects, of its clinical use including management of toxicity and an overview of the clinical results together with a description of how this internesting cytokine might be developed in the future.

Editors and Affiliations

  • Department of Oncology, Free University Hospital, Amsterdam, The Netherlands

    John Wagstaff

Bibliographic Information

  • Book Title: The role of interleukin-2 in the treatment of cancer patients

  • Editors: John Wagstaff

  • DOI: https://doi.org/10.1007/978-94-011-1753-1

  • Publisher: Springer Dordrecht

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media Dordrecht 1993

  • Hardcover ISBN: 978-0-7923-2164-4Published: 30 September 1993

  • Softcover ISBN: 978-94-010-4769-2Published: 29 October 2012

  • eBook ISBN: 978-94-011-1753-1Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: X, 191

  • Topics: Oncology, Immunology

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