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The Carnitine System

A New Therapeutical Approach to Cardiovascular Diseases

  • Book
  • © 1995

Overview

Editors:
  1. J. W. Jong

    1. Thoraxcenter, Erasmus University, Rotterdam, The Netherlands

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  2. R. Ferrari

    1. Cattedra di Cardiologia, Università degli Studi di Brescia, Fondazione Clinica del Lavoro di Pavia, Gussago/Brescia, Italy

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    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Developments in Cardiovascular Medicine (DICM, volume 162)

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Table of contents (27 chapters)

  1. Front Matter

    Pages i-xii
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  2. Introduction

    1. Introduction

      • Roberto Ferrari, Jan Willem de Jong
      Pages 1-3

  3. The carnitine system in the heart: molecular aspects

    1. Front Matter

      Pages 5-5
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    2. Carnitine-dependent pathways in heart muscle

      • Jon Bremer
      Pages 7-20

    3. Carnitine and carnitine esters in mitochondrial metabolism and function

      • Fabio Di Lisa, Roberta Barbato, Roberta Menabò, Noris Siliprandi
      Pages 21-38

    4. The effects of carnitine on myocardial carbohydrate metabolism

      • Brett O. Schönekess, Gary D. Lopaschuk
      Pages 39-52

    5. Accumulation of fatty acids and their carnitine derivatives during myocardial ischemia

      • Ger J. van der Vusse
      Pages 53-68

    6. Carnitine acylcarnitine translocase in ischemia

      • Jeanie B. Mcmillin
      Pages 69-82

    7. Amphiphilic interactions of long-chain fatty acylcarnitines with membranes: potential involvement in ischemic injury

      • Jos M. J. Lamers
      Pages 83-100

    8. Mitochondrial injury in the ischemic-reoxygenated cardiomyocyte: the role of lipids and other pathogenic factors

      • Hans Michael Piper, Thomas Noll, Berthold Siegmund
      Pages 101-121

    9. Free radical-mediated damage and carnitine esters

      • Johan Fokke Koster
      Pages 123-132

    10. Carnitine transport in volume-overloaded rat hearts

      • Josef Moravec, Zainab El Alaoui-Tablibi, Christian Brunold
      Pages 133-144

    11. Myocardial carnitine deficiency in human cardiomyopathy

      • Vera Regitz-Zagrosek, Eckart Fleck
      Pages 145-166

  4. Therapeutic efficacy of L-carnitine at the myocardial level

    1. Front Matter

      Pages 167-167
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    2. Is the carnitine system part of the heart antioxidant network?

      • Arduino Arduini, Secondo Dottori, Francesco Molajoni, Ruth Kirk, Edoardo Arrigoni-Martelli
      Pages 169-181

    3. Experimental evidence of the anti-ischemic effect of L-carnitine

      • Dennis J. Paulson, Austin L. Shug
      Pages 183-197

    4. Carnitine metabolism during diabetes and hyperthyroidy

      • Danielle Feuvray
      Pages 199-208

    5. Carnitine and lactate metabolism

      • Roberto Ferrari, Odoardo Visioli
      Pages 209-224

    6. Therapeutic potential of L-carnitine in patients with angina pectoris

      • Carl J. Pepine, Michael A. Welsch
      Pages 225-243

    7. Carnitine and myocardial infarction

      • Paolo Rizzon, Matteo Di Biase, Giuseppina Biasco, Maria Vittoria Pitzalis
      Pages 245-249
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Keywords

About this book

In the last few years, derivatives of L-carnitine, such as acetyl-L-carnitine and propionyl-L-carnitine, have been made available to doctors for treatment of specific pathologies. The effects of this family of related carnitine compounds on cardiovascular systems and diseases constitute the major issue addressed in this volume.
Although several books on carnitine have been published, a treatise focusing on experimental and clinical aspects of the carnitine family and cardiovascular diseases was lacking. The present book provides the reader with a concise update in this field. The information collected from experts on various aspects of the fascinating compound, carnitine, will be useful for both clinicians and basic scientists.

Editors and Affiliations

  • Thoraxcenter, Erasmus University, Rotterdam, The Netherlands

    J. W. Jong

  • Cattedra di Cardiologia, Università degli Studi di Brescia, Fondazione Clinica del Lavoro di Pavia, Gussago/Brescia, Italy

    R. Ferrari

Bibliographic Information

  • Book Title: The Carnitine System

  • Book Subtitle: A New Therapeutical Approach to Cardiovascular Diseases

  • Editors: J. W. Jong, R. Ferrari

  • Series Title: Developments in Cardiovascular Medicine

  • DOI: https://doi.org/10.1007/978-94-011-0275-9

  • Publisher: Springer Dordrecht

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media Dordrecht 1995

  • Hardcover ISBN: 978-0-7923-3318-0Due: 30 June 1995

  • Softcover ISBN: 978-94-010-4122-5Published: 11 January 2012

  • eBook ISBN: 978-94-011-0275-9Published: 06 December 2012

  • Series ISSN: 0166-9842

  • Edition Number: 1

  • Number of Pages: 400

  • Number of Illustrations: 33 b/w illustrations

  • Topics: Cardiology, Internal Medicine, Biochemistry, general

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