Optical Spectroscopy and Computational Methods in Biology and Medicine

1. Front Matter

   Pages i-xii

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2. Introduction

   1. Front Matter

      Pages 1-1

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   2. General Overview on Vibrational Spectroscopy Applied in Biology and Medicine

      • Malgorzata Baranska, Maciej Roman, Katarzyna Majzner

      Pages 3-14

   3. Integrating Optical Spectroscopy and Chemometric Methods

      • Karolina Jagiełło, Anita Sosnowska, Jan Mazerski, Tomasz Puzyn

      Pages 15-26

3. New Techniques and Special Applications

   1. Front Matter

      Pages 27-27

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   2. Surface-enhanced Raman Scattering (SERS) in Bioscience: A Review of Application

      • Jolanta Bukowska, Piotr Piotrowski

      Pages 29-59

   3. Raman Optical Activity of Biological Samples

      • Katarzyna Chruszcz-Lipska, Ewan W. Blanch

      Pages 61-81

   4. α-Amino Acids In Water: A Review Of VCD And ROA Spectra

      • Jan Cz. Dobrowolski, P.J.F. Lipinski, Joanna E. Rode, Joanna Sadlej

      Pages 83-160

   5. Electronic Circular Dichroism Spectroscopy in Structural Analysis of Biomolecular Systems

      • Magdalena Pecul, Wojciech Dzwolak

      Pages 161-177

   6. Biologically Relevant Molecules Studied in Low Temperature Inert Matrices

      • Rui Fausto, Nihal Kuş

      Pages 179-211

   7. Two-Dimensional Mid-Infrared Correlation Spectroscopy in Protein Research

      • Bogusława Czarnik-Matusewicz, Young Mee Jung

      Pages 213-250

4. Biological Applications

   1. Front Matter

      Pages 251-251

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   2. Qualitative and Quantitative FT-Raman Analysis of Plants

      • Hartwig Schulz

      Pages 253-278

   3. Chemometric Analysis of Raman and IR Spectra of Natural Dyes

      • Anna Rygula, Paweł Miskowiec

      Pages 279-308

   4. Structural and Spatial Analysis of Carotenoids in a Single Cell Monitored by Raman Spectroscopy

      • Agnieszka Kaczor, Marta Pilarczyk

      Pages 309-326

5. Biomedical Applications

   1. Front Matter

      Pages 327-327

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   2. Raman Spectra of Solid Amino Acids: Spectral Correlation Analysis as the First Step Towards Identification by Raman Spectroscopy

      • Tomasz Roliński, Sylwester Gawinkowski, Agnieszka Kamińska, Jacek Waluk

      Pages 329-354

   3. Vibrational Spectroscopy: Disease Diagnostics and Beyond

      • Hugh J. Byrne, Kamila M. Ostrowska, Haq Nawaz, Jennifer Dorney, Aidan D. Meade, Franck Bonnier et al.

      Pages 355-399

   4. Quantitative Analysis of Disease Biomarkers Using Surface-Enhanced Raman Scattering Spectroscopy

      • Jaebum Choo, Hyangah Chon

      Pages 401-417

   5. FTIR Imaging of Tissues: Techniques and Methods of Analysis

      • Kamilla Malek, Bayden R. Wood, Keith R. Bambery

      Pages 419-473

This multi-author contributed volume gives a comprehensive overview of recent progress in various vibrational spectroscopic techniques and chemometric methods and their applications in chemistry, biology and medicine. In order to meet the needs of readers, the book focuses on recent advances in technical development and potential exploitations of the theory, as well as the new applications of vibrational methods to problems of recent general interest that were difficult or even impossible to achieve in the not so distant past. Integrating vibrational spectroscopy and computational approaches serves as a handbook for people performing vibrational spectroscopy followed by chemometric analysis hence both experimental methods as well as procedures of recommended analysis are described. This volume is written for individuals who develop new methodologies and extend these applications to new realms of chemical and medicinal interest.

• Analytical Spectroscopy
• Chemometrics
• FT-IR Imaging
• FT-IR Spectroscopy
• Imaging, Biomolecules
• Raman Imaging
• Raman Spectroscopy
• SERS
• Vibrational Spectroscopy Techniques

• Faculty of Chemistry, Jagiellonian University, Ingardena 3, Krakow, Poland

  Malgorzata Baranska

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