Molecular Pathology and Diagnostics of Cancer

1. Front Matter

   Pages i-viii

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2. Molecular Pathology and Diagnostics of Gliomas

   • Jesse Kresak, Yuan (Frank) Shan

   Pages 1-17

3. Molecular Pathology and Diagnostics of Thyroid and Parathyroid Malignancies

   • Rodney E. Shackelford, Jason Savell

   Pages 19-55

4. Molecular Pathology and Diagnostics of Breast Cancer

   • William Kong, Ted Richards, Jin Q. Cheng, Domenico Coppola

   Pages 57-73

5. Molecular Pathology and Diagnostics of Non-small Cell Lung Carcinoma

   • Brian Quigley, Steve Ducker, Farah Khalil

   Pages 75-118

6. Molecular Pathology and Diagnostics of Colorectal Cancer

   • Rodney E. Shackelford, Aejaz Nasir, Ardeshir Hakam, David Shibata, Timothy Yeatman, Domenico Coppola

   Pages 119-175

7. Molecular Pathology and Diagnostics in Esophago-gastric Cancer

   • Rodney E. Shackelford, Maisoun Qassim Abdelbaqi, Khaldoon Almhanna, Kenneth Meredith, Domenico Coppola

   Pages 177-210

8. Molecular-Genetic Testing in Hepatocellular Carcinoma and Its Premalignant Conditions

   • Rodney E. Shackelford, Greg Mayhall, Shankar Japa, Aejaz Nasir, Mokenge Malafa, Domenico Coppola

   Pages 211-258

9. Molecular Diagnostics of Pancreatic Cancer

   • Edward J. Richards, William Kong, Mokenge Malafa, Jin Q. Cheng, Domenico Coppola

   Pages 259-282

10. Molecular Pathology and Diagnostics of Prostate Cancer

    • Rodney E. Shackelford, Janese Trimaldi, Philippe E. Spiess, Wade J. Sexton, Maisoun Qassim Abdelbaqi, Shang-Tian Chuang

    Pages 283-327

11. Molecular Diagnosis of Bladder and Kidney Cancer

    • Marino E. Leon, Dahui Qin, Debra L. Zynger

    Pages 329-340

12. Molecular-Genetic Testing in Penile, Scrotal, and Testicular Cancer

    • Nicholas A. Whitling, Sharon M. Hirsh, Rodney E. Shackelford

    Pages 341-364

13. Molecular Pathology and Diagnostics of Gynecologic Malignancies

    • Rodney E. Shackelford, Masoumeh Ghayouri, Domenico Coppola, Ardeshir Hakam

    Pages 365-395

14. Molecular Pathology of Bone and Soft Tissue Neoplasms and Potential Targets for Novel Therapy

    • Evita B. Henderson-Jackson, Anthony Conley, Marilyn M. Bui

    Pages 397-421

15. Molecular Pathology and Diagnostics of Pancreatic Endocrine Neoplasms

    • Aejaz Nasir, Jonathan R. Strosberg, Larry K. Kvols, Jalil Muhammad, Nelly A. Nasir, Omie Mills et al.

    Pages 423-448

16. Molecular Pathology and Diagnostics of Childhood Tumors

    • Enid Gilbert-Barness, Kristen Eisbrenner

    Pages 449-495

17. Molecular Pathology and Diagnostics of Cutaneous Malignancy

    • Sudeep Gaudi, Patricia M. McNab, Timothy W. McCardle, Jane L. Messina

    Pages 497-519

18. Molecular Diagnostics of Lymphoid Neoplasms

    • Deniz Peker, Jianguo Tao, Ling Zhang

    Pages 521-555

19. Molecular Diagnostics of Myeloid Neoplasms

    • Xiaohui Zhang, Ling Zhang

    Pages 557-587

20. Back Matter

    Pages 589-601

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Molecular pathology is based on the emergence of new techniques that greatly enhance the diagnostic accuracy when facing with challenging differential diagnoses. In addition, new molecular techniques are entering the clinical arena for their value in predicting therapy response and tumor prognosis. This book provides a guide for the practicing pathologist and for both pathology residents and fellows during the daily sign-out of challenging cases. The book is organized by anatomical systems and provides a detailed description of molecular tests that may help in the diagnosis. Furthermore, a description of the current molecular tests required to identify patients for treatment is offered. The application of molecular pathology techniques to the clinical practice has already shown its usefulness and the number of such tests is growing exponentially as more molecular targets are discovered. Molecular Pathology and Diagnostics of Cancer will give practicing and training pathologists an up-to date resource to guide the correct management of pathology cases requiring molecular testing.

• Cancer
• Diagnosis
• Molecular testing
• Pathology
• Prognosis

From the reviews:

“This is a comprehensive book on current molecular tests and the recent advances in the field of diagnostics. … The intended audience includes students, pathologists, oncologists, cancer scientists, and other professionals interested in molecular pathology of cancer. … this book is by far the most comprehensive resource in its field. In particular, it is useful for pathologists and oncologists during their daily signout of challenging cases. This book is a great contribution to the field of pathology.” (Aida I. Richardson, Doody’s Book Reviews, May, 2014)

• Anatomic Pathology, University of South Florida, Moffitt Cancer Center, Tampa, USA

  Domenico Coppola

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