Quantitative Ultrasound in Soft Tissues

1. Front Matter

   Pages i-xvi

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2. Ultrasound Backscatter Coefficient

   1. Front Matter

      Pages 1-1

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   2. State of the Art Methods for Estimating Backscatter Coefficients

      • Goutam Ghoshal, Jonathan Mamou, Michael L. Oelze

      Pages 3-19

   3. Quantitative Ultrasound History and Successes

      • Goutam Ghoshal, Michael L. Oelze, William D. O’Brien Jr.

      Pages 21-42

   4. Statistics of Scatterer Property Estimates

      • Michael L. Oelze

      Pages 43-69

   5. Attenuation Compensation and Estimation

      • Timothy A. Bigelow, Yassin Labyed

      Pages 71-93

   6. Quantitative Ultrasound and Cell Death

      • Omar Falou, Ali Sadeghi-Naini, Azza Al-Mahrouki, Michael C. Kolios, Gregory J. Czarnota

      Pages 95-115

   7. Modeling of Ultrasound Backscattering by Aggregating Red Blood Cells

      • Emilie Franceschini, Guy Cloutier

      Pages 117-145

   8. Backscatter Quantification for the Detection of Metastatic Regions in Human Lymph Nodes

      • Jonathan Mamou, Alain Coron, Emi Saegusa-Beecroft, Masaki Hata, Eugene Yanagihara, Junji Machi et al.

      Pages 147-170

   9. Quantitative Ultrasound for Tissue-type Imaging of the Prostate: Implications for Planning and Guiding Biopsies and Delivering Focal Treatments

      • Ernest J. Feleppa, Christopher R. Porter

      Pages 171-192

   10. Therapy Monitoring and Assessment Using Quantitative Ultrasound

       • Michael L. Oelze, Jeremy P. Kemmerer, Goutam Ghoshal, Roxana M. Vlad

       Pages 193-216

3. Envelope Statistics

   1. Front Matter

      Pages 217-217

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   2. Review of Envelope Statistics Models for Quantitative Ultrasound Imaging and Tissue Characterization

      • François Destrempes, Guy Cloutier

      Pages 219-274

   3. The Quantitative Ultrasound Diagnosis of Liver Fibrosis Using Statistical Analysis of the Echo Envelope

      • Tadashi Yamaguchi

      Pages 275-288

4. Scanning Acoustic Microscopy

   1. Front Matter

      Pages 289-289

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   2. Recent Applications of Acoustic Microscopy for Quantitative Measurement of Acoustic Properties of Soft Tissues

      • Yoshifumi Saijo

      Pages 291-313

   3. Acoustic Microscopy of Cells

      • Michael C. Kolios, Eric M. Strohm, Gregory J. Czarnota

      Pages 315-341

5. Ultrasound Computer Tomography

   1. Front Matter

      Pages 343-343

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   2. Methods for Forward and Inverse Scattering in Ultrasound Tomography

      • Roberto J. Lavarello, Andrew J. Hesford

      Pages 345-394

   3. Clinical Results with Ultrasound Computed Tomography of the Breast

      • Michael André, James Wiskin, David Borup

      Pages 395-432

Due to parallel advances in signal processing and computer hardware in the last 15 years, quantitative ultrasound techniques have reached maturity, allowing for the construction of quantitative maps or images of soft tissues. This book will focus on 5 modern research topics related to quantitative ultrasound of soft tissues: - Spectral-based methods for tissue characterization, tissue typing, cancer detection, etc.; - Envelope statistics analysis as a means of quantifying and imaging tissue properties; - Ultrasound elastography for quantifying elastic properties of tissues (several clinical ultrasound scanners now display elastography images); - Scanning acoustic microscopy for forming images of mechanical properties of soft tissues with micron resolution (desktop size scanners are now available); and - Ultrasound computer tomography for breast cancer imaging (new ultrasound tomography systems have been developed and are currently under evaluation clinically).

• Acoustic microscopy
• Backscatter
• Quantitative ultrasound
• Tissue characterization
• Ultrasound methods

From the reviews:

“The editors made an excellent choice of their collection of methods and applications in this rapidly evolving QUS research field. Therefore the reader whatever pre-knowledge he comes with will find basic or advanced information in this book. For newcomers to this topic the book is very suitable to get an excellent understanding for the basic and statistical methods used in QUS … . This book is recommended for lecturers or teachers … .” (Christian Kollmann, Ultraschall in der Medizin European Journal of Ultrasound, Vol. 35 (2), April, 2014)

• Biomedical Engineering, Riverside Research Institute F.L. Lizzi Center, New York, USA

  Jonathan Mamou

• Electrical and Computer Engineering, University of Illinois at Urbana-Champaign, Urbana, USA

  Michael L. Oelze

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