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Lipid-mediated Protein Signaling

  • Book
  • © 2013

Overview

Editors:
  1. Daniel G.S. Capelluto

    1. , Biological Sciences, Virginia Tech, Blacksburg, USA

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  • Summarizes innovative research in lipid-mediated signaling
  • Presents contributions from internationally recognized scientists
  • Offers a valuable resource for cell biologists, structural biologists, and pharmacologists with interest in lipid signaling
  • Emphasizes on sphingolipid- and phospholipid-mediated protein signaling
  • Examines lipid signaling from plasma membrane and intracellular organelles

Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 991)

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Table of contents (11 chapters)

  1. Front Matter

    Pages i-xiii
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  2. Sphingomyelin and Its Role in Cellular Signaling

    • Mahua Chakraborty, Xian-Cheng Jiang
    Pages 1-14

  3. The Driving Force of Alpha-Synuclein Insertion and Amyloid Channel Formation in the Plasma Membrane of Neural Cells: Key Role of Ganglioside- and Cholesterol-Binding Domains

    • Jacques Fantini, Nouara Yahi
    Pages 15-26

  4. The Enigmatic Role of Sulfatides: New Insights into Cellular Functions and Mechanisms of Protein Recognition

    • Shuyan Xiao, Carla V. Finkielstein, Daniel G. S. Capelluto
    Pages 27-40

  5. Phosphoinositides and PDZ Domain Scaffolds

    • Anna Maria Wawrzyniak, Rudra Kashyap, Pascale Zimmermann
    Pages 41-57

  6. PtdIns(4)P Signalling and Recognition Systems

    • Marc Lenoir, Michael Overduin
    Pages 59-83

  7. PtdIns(4,5)P2-Mediated Cell Signaling: Emerging Principles and PTEN as a Paradigm for Regulatory Mechanism

    • Arne Gericke, Nicholas R. Leslie, Mathias Lösche, Alonzo H. Ross
    Pages 85-104

  8. Role of Phosphatidylinositol 3,4,5-Trisphosphate in Cell Signaling

    • Robert D. Riehle, Sinziana Cornea, Alexei Degterev
    Pages 105-139

  9. The Role of Phosphoinositides and Inositol Phosphates in Plant Cell Signaling

    • Glenda E. Gillaspy
    Pages 141-157

  10. Phosphatidic Acid-Mediated Signaling

    • Yu Liu, Yuan Su, Xuemin Wang
    Pages 159-176

  11. Phosphatidylserine-Mediated Cellular Signaling

    • Jason G. Kay, Sergio Grinstein
    Pages 177-193

  12. Cardiolipin-Mediated Cellular Signaling

    • Vinay A. Patil, Miriam L. Greenberg
    Pages 195-213

  13. Back Matter

    Pages 215-219
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Keywords

About this book

This book provides the most updated information of how membrane lipids mediate protein signaling from studies carried out in animal and plant cells. Also, there are some chapters that go beyond and expand these studies of protein-lipid interactions at the structural level. The book begins with a literature review from investigations associated to sphingolipids, followed by studies that describe the role of phosphoinositides in signaling and closing with the function of other key lipids in signaling at the plasma membrane and intracellular organelles.

Editors and Affiliations

  • , Biological Sciences, Virginia Tech, Blacksburg, USA

    Daniel G.S. Capelluto

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