Cancer Genomics
Molecular Classification, Prognosis and Response Prediction
Editors: Pfeffer, Ulrich (Ed.)
Free Preview- Comprehensive review of the field, none yet published
- Critical reviews written by outstanding investigators with no personal interest in the applications
- Easy to understand for clinicians and researchers who wish to obtain an overview over the rapidly evolving field
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- About this book
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The combination of molecular biology, engineering and bioinformatics has revolutionized our understanding of cancer revealing a tight correlation of the molecular characteristics of the primary tumor in terms of gene expression, structural alterations of the genome, epigenetics and mutations with its propensity to metastasize and to respond to therapy. It is not just one or a few genes, it is the complex alteration of the genome that determines cancer development and progression. Future management of cancer patients will therefore rely on thorough molecular analyses of each single case.
Through this book, students, researchers and oncologists will obtain a comprehensive picture of what the first ten years of cancer genomics have revealed. Experts in the field describe, cancer by cancer, the progress made and its implications for diagnosis, prognosis and treatment of cancer. The deep impact on the clinics and the challenge for future translational research become evident.
- Table of contents (17 chapters)
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Genomic Pathology of Lung Cancer
Pages 1-46
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Understanding Melanoma Progression by Gene Expression Signatures
Pages 47-78
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Prognostic Testing in Uveal Melanoma
Pages 79-96
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Capturing and Deciphering the Molecular Signatures of Head and Neck Cancer
Pages 97-130
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Predictive and Prognostic Biomarkers for Colorectal Cancer
Pages 131-162
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Table of contents (17 chapters)
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Bibliographic Information
- Bibliographic Information
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- Book Title
- Cancer Genomics
- Book Subtitle
- Molecular Classification, Prognosis and Response Prediction
- Editors
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- Ulrich Pfeffer
- Copyright
- 2013
- Publisher
- Springer Netherlands
- Copyright Holder
- Springer Science+Business Media Dordrecht
- eBook ISBN
- 978-94-007-5842-1
- DOI
- 10.1007/978-94-007-5842-1
- Hardcover ISBN
- 978-94-007-5841-4
- Softcover ISBN
- 978-94-007-9802-1
- Edition Number
- 1
- Number of Pages
- VI, 588
- Number of Illustrations
- 56 b/w illustrations, 61 illustrations in colour
- Topics