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Advances in Experimental Medicine and Biology

Isotope labeling in Biomolecular NMR

Editors: Atreya, Hanudatta S. (Ed.)

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  • Includes step-by-step procedures and practical tips for different isotope labeling methods
  • Covers the entire gamut of biomolecular NMR spectroscopy
  • Includes emerging areas such as structure/dynamics of large proteins, metabolomics and solid state NMR
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eBook $139.00
price for USA in USD (gross)
  • ISBN 978-94-007-4954-2
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $199.99
price for USA in USD
  • ISBN 978-94-007-4953-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $179.99
price for USA in USD
  • ISBN 978-94-024-0646-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

NMR spectroscopy has undergone a revolution in recent years with the advent of several new methods overcoming the problems of sensitivity and resolution. Recent developments in biotechnology have made it easier and economical to introduce 13C, 15N and 2H into proteins and nucleic acids. At the same time, there has been an explosion in the number of NMR experiments that utilize such isotope labeled samples. Thus, a combination of isotopic labeling and multidimensional, multinuclear NMR has opened up new avenues for structural studies of proteins, nucleic acids and their complexes.

This book will focus on recent developments in isotope labeling methods for structural studies of small molecules, peptides, proteins and nucleic acids. The aim of the book is to serve as a compendium of isotope labeling for the biomolecular NMR community providing comprehensive coverage of the existing methods and latest developments along with protocols and practical hints on the various experimental aspects. The book will cover a wide range of topics in isotope labeling under one title including emerging areas of metabolonomics and solid state NMR.

Table of contents (11 chapters)

Table of contents (11 chapters)
  • Isotope Labeling Methods for Large Systems

    Pages 3-15

    Lundström, Patrik (et al.)

  • Segmental Labeling to Study Multidomain Proteins

    Pages 17-33

    Xue, Jing (et al.)

  • Isotope Labeling for Solution and Solid-State NMR Spectroscopy of Membrane Proteins

    Pages 35-62

    Verardi, Raffaello (et al.)

  • Isotope Labeling Methods for Relaxation Measurements

    Pages 63-82

    Lundström, Patrik (et al.)

  • Stereo-Array Isotope Labeling Method for Studying Protein Structure and Dynamics

    Pages 83-93

    Miyanoiri, Yohei (et al.)

Buy this book

eBook $139.00
price for USA in USD (gross)
  • ISBN 978-94-007-4954-2
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $199.99
price for USA in USD
  • ISBN 978-94-007-4953-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $179.99
price for USA in USD
  • ISBN 978-94-024-0646-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Isotope labeling in Biomolecular NMR
Editors
  • Hanudatta S. Atreya
Series Title
Advances in Experimental Medicine and Biology
Series Volume
992
Copyright
2012
Publisher
Springer Netherlands
Copyright Holder
Springer Science+Business Media Dordrecht
eBook ISBN
978-94-007-4954-2
DOI
10.1007/978-94-007-4954-2
Hardcover ISBN
978-94-007-4953-5
Softcover ISBN
978-94-024-0646-7
Series ISSN
0065-2598
Edition Number
1
Number of Pages
VIII, 219
Topics