Sarcopenia – Age-Related Muscle Wasting and Weakness
Mechanisms and Treatments
Editors: Lynch, Gordon S. (Ed.)
Free Preview- State-of-the-art information on aging and skeletal muscle
- Contributions from some of the world’s leading experts in skeletal muscle aging
- Identifies key neuromuscular mechanisms responsible for sarcopenia
- Identifies signalling pathways and targets for therapeutic intervention
- Information has relevance and broad application for researchers and practitioners involved with the study and treatment of aging and its effects on skeletal muscle
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- About this book
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Some of the most serious consequences of aging are its effects on skeletal muscle. ‘Sarcopenia’, the progressive age-related loss of muscle mass and associated muscle weakness, renders frail elders susceptible to serious injury from sudden falls and fractures and at risk for losing their functional independence. Not surprisingly, sarcopenia is a significant public health problem throughout the developed world. There is an urgent need to better understand the neuromuscular mechanisms underlying age-related muscle wasting and to develop therapeutic strategies that can attenuate, prevent, or ultimately reverse sarcopenia. Significant research and development in academic and research institutions and in pharmaceutical companies is being directed to sarcopenia and to related health issues in order to develop and evaluate novel therapeutics. This book provides the latest information on sarcopenia from leading international researchers studying the cellular and molecular mechanisms underlying age-related changes in skeletal muscle and identifies strategies to combat sarcopenia and related muscle wasting conditions and neuromuscular disorders. The book provides a vital resource for researchers and practitioners alike, with information relevant to gerontologists, geriatricians, sports medicine physicians, physiologists, neuroscientists, cell biologists, endocrinologists, physical therapists, allied health and musculoskeletal practitioners, strength and conditioning specialists, athletic trainers, and students of the medical and biomedical sciences.
- Table of contents (19 chapters)
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Overview of Sarcopenia
Pages 1-7
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Muscle Wasting in Cancer and Ageing: Cachexia Versus Sarcopenia
Pages 9-35
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Age-Related Remodeling of Neuromuscular Junctions
Pages 37-54
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Aging-Related Changes Motor Unit Structure and Function
Pages 55-74
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Age-Related Decline in Actomyosin Structure and Function
Pages 75-111
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Table of contents (19 chapters)
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Bibliographic Information
- Bibliographic Information
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- Book Title
- Sarcopenia – Age-Related Muscle Wasting and Weakness
- Book Subtitle
- Mechanisms and Treatments
- Editors
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- Gordon S. Lynch
- Copyright
- 2011
- Publisher
- Springer Netherlands
- Copyright Holder
- Springer Science+Business Media B.V.
- eBook ISBN
- 978-90-481-9713-2
- DOI
- 10.1007/978-90-481-9713-2
- Hardcover ISBN
- 978-90-481-9712-5
- Softcover ISBN
- 978-94-007-9044-5
- Edition Number
- 1
- Number of Pages
- XIII, 479
- Topics
