Functional and Structural Proteomics of Glycoproteins
Editors: Owens, Raymond J., Nettleship, Joanne E. (Eds.)
Free Preview- Shows how glyco-engineering coupled to rapid recombinant protein production has facilitated the determination of glycoprotein structures
- Provides a review of the state of the art in glycoproteomics
- Written by experts in the field
Buy this book
- About this book
-
It has been predicted that nearly half of all human proteins are glycosylated indicating the significance of glycoproteins in human health and disease. For example, the glycans attached to proteins have emerged as important biomarkers in the diagnosis of diseases such as cancers and play a significant role in how pathogenic viruses gain entry into human cells. The study of glycoproteins has now become a truly proteomic science. In the last few years, technology developments including in silico methods, high throughput separation and detection techniques have accelerated the characterization of glycoproteins in cells and tissues. Glyco-engineering coupled to rapid recombinant protein production has facilitated the determination of glycoprotein structures key to exploring and exploiting their functional roles. Each chapter in this volume is written by experts in the field and together provide a review of the state of the art in the emerging field of glycoproteomics.
- Table of contents (7 chapters)
-
-
Glycoproteomics in Health and Disease
Pages 1-38
-
Glyco-engineering of Fc Glycans to Enhance the Biological Functions of Therapeutic IgGs
Pages 39-58
-
Bioinformatics Databases and Applications Available for Glycobiology and Glycomics
Pages 59-90
-
Lectin Microarrays: Simple Tools for the Analysis of Complex Glycans
Pages 91-102
-
The Application of High Throughput Mass Spectrometry to the Analysis of Glycoproteins
Pages 103-125
-
Table of contents (7 chapters)
Recommended for you
Bibliographic Information
- Bibliographic Information
-
- Book Title
- Functional and Structural Proteomics of Glycoproteins
- Editors
-
- Raymond J. Owens
- Joanne E. Nettleship
- Copyright
- 2011
- Publisher
- Springer Netherlands
- Copyright Holder
- Springer Science+Business Media B.V.
- eBook ISBN
- 978-90-481-9355-4
- DOI
- 10.1007/978-90-481-9355-4
- Hardcover ISBN
- 978-90-481-9354-7
- Softcover ISBN
- 978-94-007-9040-7
- Edition Number
- 1
- Number of Pages
- X, 181
- Topics
