Functional and Structural Proteomics of Glycoproteins

Editors: Owens, Raymond J., Nettleship, Joanne E. (Eds.)

Free Preview
  • Shows how glyco-engineering coupled to rapid recombinant protein production has facilitated the determination of glycoprotein structures
  • Provides a review of the state of the art in glycoproteomics
  • Written by experts in the field
see more benefits

Buy this book

eBook $149.00
price for USA in USD
  • ISBN 978-90-481-9355-4
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • Immediate eBook download after purchase and usable on all devices
  • Bulk discounts available
Hardcover $219.99
price for USA in USD
Softcover $199.99
price for USA in USD
About this book

It has been predicted that nearly half of all human proteins are glycosylated indicating the significance of glycoproteins in human health and disease. For example, the glycans attached to proteins have emerged as important biomarkers in the diagnosis of diseases such as cancers and play a significant role in how pathogenic viruses gain entry into human cells. The study of glycoproteins has now become a truly proteomic science. In the last few years, technology developments including in silico methods, high throughput separation and detection techniques have accelerated the characterization of glycoproteins in cells and tissues. Glyco-engineering coupled to rapid recombinant protein production has facilitated the determination of glycoprotein structures key to exploring and exploiting their functional roles. Each chapter in this volume is written by experts in the field and together provide a review of the state of the art in the emerging field of glycoproteomics.

Table of contents (7 chapters)

Table of contents (7 chapters)
  • Glycoproteomics in Health and Disease

    Pages 1-38

    Struwe, Weston B. (et al.)

  • Glyco-engineering of Fc Glycans to Enhance the Biological Functions of Therapeutic IgGs

    Pages 39-58

    Raju, T. Shantha (et al.)

  • Bioinformatics Databases and Applications Available for Glycobiology and Glycomics

    Pages 59-90

    Ranzinger, René (et al.)

  • Lectin Microarrays: Simple Tools for the Analysis of Complex Glycans

    Pages 91-102

    Krishnamoorthy, Lakshmi (et al.)

  • The Application of High Throughput Mass Spectrometry to the Analysis of Glycoproteins

    Pages 103-125

    Singh, Sasha (et al.)

Buy this book

eBook $149.00
price for USA in USD
  • ISBN 978-90-481-9355-4
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • Immediate eBook download after purchase and usable on all devices
  • Bulk discounts available
Hardcover $219.99
price for USA in USD
Softcover $199.99
price for USA in USD
Loading...

Recommended for you

Loading...

Bibliographic Information

Bibliographic Information
Book Title
Functional and Structural Proteomics of Glycoproteins
Editors
  • Raymond J. Owens
  • Joanne E. Nettleship
Copyright
2011
Publisher
Springer Netherlands
Copyright Holder
Springer Science+Business Media B.V.
eBook ISBN
978-90-481-9355-4
DOI
10.1007/978-90-481-9355-4
Hardcover ISBN
978-90-481-9354-7
Softcover ISBN
978-94-007-9040-7
Edition Number
1
Number of Pages
X, 181
Topics