Apoptosome

An up-and-coming therapeutical tool

Editors: Cecconi, Francesco, D'Amelio, Marcello (Eds.)

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  • Provides an authoritative review of this highly active area of research on programmed cell death
  • Discusses issues of significance of apoptosome such as its structure, composition and regulation
  • Reviews the preclinical and clinical applications of apoptosome regulation
  • A useful resource for molecular and cell biologists, as well as for scientist and the academic/industry community
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eBook $149.00
price for USA in USD (gross)
  • ISBN 978-90-481-3415-1
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $249.99
price for USA in USD
  • ISBN 978-90-481-3414-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $199.99
price for USA in USD
  • ISBN 978-94-007-9090-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

"Apoptosome" is the first book that presents a concise synthesis of recent developments in the understanding of how the activation of the cell death cascade is handled by a cytosolic signalling platform known as the apoptosome.

The book also discusses how insights into the regulation of apoptosome may be exploited for designing new drugs aimed at interfere with a plethora of pathogenetic processes involved in human diseases.

The authors emphasize novel translational approaches that are rapidly moving from the laboratory bench top to the patient's bedside for the future treatment of diseases associated with apoptosis.

This book will be a valuable resource for researchers investigating the role of apoptosome-dependent cell death in cancer and other diseases, for researchers investigating the molecular mechanism of chemotherapeutic agents and drug-resistance and for physicians using chemotherapeutic agents. Additionally, this book will be an important educational source for PhD students and MD students specializing in molecular and cell biology, and to anybody interested in science, medicine, as well as in recent developments of the ideas and concepts of the molecular biology of programmed cell death.

Table of contents (16 chapters)

Table of contents (16 chapters)
  • Physiological and Pathological Role of Apoptosis

    Cavallucci, Virve (et al.)

    Pages 1-26

  • Apoptosome Structure and Regulation

    Ferraro, Elisabetta (et al.)

    Pages 27-39

  • Chemical Regulation of the Apoptosome: New Alternative Treatments for Cancer

    Cain, Kelvin

    Pages 41-74

  • Molecules That Bind a Central Protein Component of the Apoptosome, Apaf-1, and Modulate Its Activity

    Mondragón, Laura (et al.)

    Pages 75-94

  • Regulation of Cell Death and Survival by RNA Interference – The Roles of miRNA and siRNA

    Lingor, Paul

    Pages 95-117

Buy this book

eBook $149.00
price for USA in USD (gross)
  • ISBN 978-90-481-3415-1
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $249.99
price for USA in USD
  • ISBN 978-90-481-3414-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $199.99
price for USA in USD
  • ISBN 978-94-007-9090-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Apoptosome
Book Subtitle
An up-and-coming therapeutical tool
Editors
  • Francesco Cecconi
  • Marcello D'Amelio
Copyright
2010
Publisher
Springer Netherlands
Copyright Holder
Springer Science+Business Media B.V.
eBook ISBN
978-90-481-3415-1
DOI
10.1007/978-90-481-3415-1
Hardcover ISBN
978-90-481-3414-4
Softcover ISBN
978-94-007-9090-2
Edition Number
1
Number of Pages
X, 322
Topics