Single Subject Designs in Biomedicine

1. Front Matter

   Pages i-xiii

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2. Overview of the Single Subject Design

   • Janine E. Janosky, Shelley L. Leininger, Michael P. Hoerger, Terry M. Libkuman

   Pages 1-7

3. The Application of the Single Subject Design

   • Janine E. Janosky, Shelley L. Leininger, Michael P. Hoerger, Terry M. Libkuman

   Pages 9-24

4. Methodological Framework for Single Subject Designs

   • Janine E. Janosky, Shelley L. Leininger, Michael P. Hoerger, Terry M. Libkuman

   Pages 25-43

5. Evaluation and Analysis of Data Generated from Single Subject Designs

   • Janine E. Janosky, Shelley L. Leininger, Michael P. Hoerger, Terry M. Libkuman

   Pages 45-68

6. Ethics and Single Subject Research

   • Janine E. Janosky, Shelley L. Leininger, Michael P. Hoerger, Terry M. Libkuman

   Pages 69-80

7. Application of the Single Subject Design in Biomedicine

   • Janine E. Janosky, Shelley L. Leininger, Michael P. Hoerger, Terry M. Libkuman

   Pages 81-96

8. Annotated Bibliography of Single Subject Studies

   • Janine E. Janosky, Shelley L. Leininger, Michael P. Hoerger, Terry M. Libkuman

   Pages 97-122

9. Back Matter

   Pages 123-124

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Single Subject Designs in Biomedicine draws upon the rich history of single case research within the educational and behavioral research settings and extends the application to the field of biomedicine. Biomedical illustrations are used to demonstrate the processes of designing, implementing, and evaluating a single subject design. Strengths and limitations of various methodologies are presented, along with specific clinical areas of application in which these applications would be appropriate. Statistical and visual techniques for data analysis are also discussed. The breadth and depth of information provided is suitable for medical students in research oriented courses, primary care practitioners and medical specialists seeking to apply methods of evidence practice to improve patient care, and medical researchers who are expanding their methodological expertise to include single subject designs. Increasing awareness of the utility in the single subject design could enhance treatment approach and evaluation both in biomedical research and medical care settings.

• Biomedicine
• Case study
• Measure
• N-of-1
• Patient care research
• Research methodology
• Single subject designs
• data analysis
• instrumentation
• methodology

From the reviews: “This book focuses on how to study the single patient. This unique contribution to research design starts with application and then discusses the methods. … Medical students and primary care and specialty practitioners are the intended audience. The book is suitable for these readers, but also for those developing new interventions and those evaluating individual patient response. … The design presented in this book has expanded its utility and this book describes it well.” (James C. Torner, Doody’s Review Service, March, 2010)

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