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Regulatory Function of Adenosine

Proceedings of the International Symposium on Adenosine, Charlottesville, Virginia, June 7–11,1982

  • Conference proceedings
  • © 1983

Overview

Editors:
  1. Robert M. Berne

    1. Department of Physiology, University of Virginia School of Medicine, Charlottesville, USA

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  2. Theodore W. Rall

    1. Department of Pharmacology, University of Virginia School of Medicine, Charlottesville, USA

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    You can also search for this editor in PubMed   Google Scholar

  3. Rafael Rubio

    1. Department of Physiology, University of Virginia School of Medicine, Charlottesville, USA

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Part of the book series: Developments in Pharmacology (DIPH, volume 2)

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Table of contents (30 papers)

  1. Front Matter

    Pages i-xxi
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  3. Adenosine Metabolism and Transport

    1. Front Matter

      Pages 115-115
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    2. Regulation of Adenosine Metabolism by 5’-Nucleotidases

      • John M. Lowenstein, Ming-Kun Yu, Yoshitsugo Naito
      Pages 117-131

    3. Metabolism of Adenosine and Sites of Production in the Heart

      • J. Schrader
      Pages 133-156

    4. Interaction of Adenosine with Adenosine-Binding Protein, S-Adenosylhomocysteine Hydrolase

      • Per Magne Ueland
      Pages 157-170

    5. S-Adenosylhomocysteine Hydrolase as a Target in Genetic and Drug-Induced Deficiency of Adenosine Deaminase

      • Michael S. Hershfield
      Pages 171-178

    6. Nucleoside Transport in Mammalian Cells and Interaction with Intracellular Metabolism

      • Peter G. W. Plagemann, Robert M. Wohlhueter
      Pages 179-201

    7. Inhibition of Nucleoside Transport

      • Alan R. P. Paterson, Ewa S. Jakobs, Eric R. Harley, Nai-Wu Fu, Morris J. Robins, Carol E. Cass
      Pages 203-220

  4. Adenosine and Regulation of Immune Function

    1. Front Matter

      Pages 221-221
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    2. Mechanisms of Toxicity of Adenosine, 2’-Deoxyadenosine, and Inhibitors of Adenosine Deaminase

      • J. Frank Henderson
      Pages 223-234

    3. Clinical Expression of Blocks of Purine Nucleotide Degradation

      • Irving H. Fox
      Pages 235-247

    4. Adenosine and Cyclic Nucleotides in Modulation of Immune Responses

      • Stephen H. Polmar, Ruth E. Birch, Raya Mandler, Stephen A. Rudolph
      Pages 249-259
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Keywords

About this book

The principal objective of this symposium was to bring together investigators from all over the world who work in diverse areas of research but share a common interest in the physiologic and pathophysiologic funetions of the nueleoside adenosine. In 1978, the "International Conference on Physiological and Regulatory Funetions of Adenosine and Adenine Nueleotides," held in Banff, Canada, served as an effective catalyst in enabling scientists with differ­ ent points of view to exchange information and ideas on this subject. Since 1978, the amount of research on different as peets of adenosine metabolism, mechanism of action, transport, and function in various tissues (in both nor­ maI and abnormal states) has increased exponentially, and there was an urgent need for another meeting for updating information on this burgeoning subject. The focus of the meeting was extremely sharp, but the scope of the subject material was very broad. Scientists categorized as chemists, biochemists, physiologists, pharmacologists, and immunologists, working with cells and eelI fragments, with tissues such as heart, brain, musele, fat, kidney, and with human beings having immune deficiency diseases participated in the sym­ posium. They had an opportunity to air their differences, reinforce their areas of agreement, and, most important, they educated each other with respeet to research on adenosine; it is hoped that they also enriched their own research programs from the information they gained from their fellow participants.

Editors and Affiliations

  • Department of Physiology, University of Virginia School of Medicine, Charlottesville, USA

    Robert M. Berne, Rafael Rubio

  • Department of Pharmacology, University of Virginia School of Medicine, Charlottesville, USA

    Theodore W. Rall

Bibliographic Information

  • Book Title: Regulatory Function of Adenosine

  • Book Subtitle: Proceedings of the International Symposium on Adenosine, Charlottesville, Virginia, June 7–11,1982

  • Editors: Robert M. Berne, Theodore W. Rall, Rafael Rubio

  • Series Title: Developments in Pharmacology

  • DOI: https://doi.org/10.1007/978-1-4613-3909-0

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Martinus Nijhoff Publishers, The Hague 1983

  • Hardcover ISBN: 978-90-247-2779-7Published: 30 April 1983

  • Softcover ISBN: 978-1-4613-3911-3Published: 17 October 2011

  • eBook ISBN: 978-1-4613-3909-0Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: XXI, 558

  • Topics: Pharmacology/Toxicology

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