Contrast-Enhanced Ultrasound of Liver Diseases

1. Front Matter

   Pages I-XII

   PDF

2. Contrast Ultrasound Technology

   • P. N. Burns

   Pages 1-19

3. Ultrasound Contrast Agents

   • A. Bauer, L. Solbiati

   Pages 21-26

4. Liver Physiology

   • D. Becker

   Pages 27-36

5. Macro- and Microcirculation of Focal Liver

   • A. Martegani, L. Aiani, C. Borghi, L. Solbiati, M. Tonolini, A. Bellobuono et al.

   Pages 37-93

6. Medical Needs

   • E. Leen

   Pages 95-101

7. Guidance and Control of Percutaneous Treatments

   • L. Solbiati, M. Tonolini, L. Cova

   Pages 103-113

8. Hands-on Contrast Ultrasound

   • J. M. Correas, O. Hélénon

   Pages 115-123

In the last few years, the development of sonographic contrast agents - or "microbubbles" - has stimulated increasingly intensive studies on the rela­ tionships between ultrasound and contrast media. As a result, "contrast -spe­ cific" hardware and software systems have been introduced by different ultra­ sound manufacturers with impressive speed. This has finally led to the birth of a very new imaging modality -"contrast-enhanced sonography" (CEUS). Since 1999, the introduction of second-generation contrast agents has represented a decisive step towards the extensive clinical use of CEUS and has simultaneously made obsolete most, if not all, scientific publications available so far. This book is, to our knowledge, the first to deal entirely with second­ generation contrast agents and the most updated contrast-specific software for noncardiologic uses. The reasons why the liver has been chosen as the only "target" of the book are easily understandable by radiologists and hepatologists alike. The study of vascularity is the only purpose of CEUS, and the liver has a unique vascular system, with two different inflow systems resulting in a single outflow. Furthermore, the pathologically different focal liver lesions (FLLs) are mostly characterized by different "models" of vascularity: CEUS can mimic contrast­ enhanced computed tomography and magnetic resonance imaging, basing differential diagnosis on the morphological and temporal characteristics of enhancement, but with the additional unique advantage of the study being done in real-time.

• Contrast-enhanced sonography
• Focal Liver Lesions
• Hepatocellular carcinoma
• Radiofrequency ablation
• carcinoma
• cell
• imaging
• liver
• liver disease
• metastasis
• pharmacology
• sonography
• ultrasound
• Ultrasonography
• hepatology

• Dept. of Radiology, General Hospital, Busto Arsizio (VA), Italy

  Luigi Solbiati

• Servizio di Radiologia, Ospedale Valduce, Como, Italy

  Alberto Martegani

• Dept. of Radiology Royal Infirmary, University of Glasgow, Glasgow, UK

  Edward Leen

• Service de Radiologie Adulte, Hôpital Necker Enfants Malades, Paris Cédex 15, France

  Jean Michel Correas

• Depts. of Medical Biophysics and Radiology, University of Toronto Sunnybrook and Women’s Health Sciences Centre, Canada

  Peter N. Burns

• Dept. of Medicine Gastroenterology, Intensive Care Medicine Eckernförde Community Hospital, Eckernförde, Germany

  Dirk Becker

Policies and ethics