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  • © 2014

Melatonin and Melatonergic Drugs in Clinical Practice

  • Book covers science & clinical significance of Melatonin and role of agonists such as ramelteon & agomelatine

  • As compared to previous books, this book provides more topics of direct clinical relevance to clinicians and researchers

  • Chapters contributed by global experts engaged in melatonin studies working in reputed universities, research foundations and laboratories

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Table of contents (29 chapters)

  1. Front Matter

    Pages i-xvii
  2. Melatonin Receptors and Their Role in Human Diseases

    • Cem Ekmekcioglu, Theresia Thalhammer
    Pages 1-15
  3. Past, Present, and Future of Melatonin’s Clinical Uses

    • Nori Tolosa de Talamoni, Vanessa Andrea Areco, Maria Elena Peralta Lopez, Gabriela Diaz de Barboza, Maria Angelica Rivoira, Agata Rita Carpentieri
    Pages 27-42
  4. Melatonin: Its Microbicidal Properties and Clinical Applications

    • Venkataramanujam Srinivasan, Mahaneem Mohamed, Hisanori Kato
    Pages 57-69
  5. Melatonin and the Metabolic Syndrome

    • Frederic Nduhirabandi, Amanda Lochner
    Pages 71-95
  6. Multiple Facets of Melatonin in Immunity: Clinical Applications

    • Patricia J. Lardone, Nuria Álvarez-Sánchez, Ana Rodríguez-Rodríguez, Juan M. Guerrero, Antonio Carrillo-Vico
    Pages 117-141
  7. Melatonin and Immune Function: Clinical Significance

    • Mahaneem Mohamed, Venkataramanujam Srinivasan, Georges Maestroni, Ruth E. Rosenstein, Sukru Oter
    Pages 143-157
  8. Melatonin and Melatonergic Drugs for Therapeutic Use in Breast Cancer

    • Emilio J. Sanchez-Barcelo, Maria D. Mediavilla Aguado, Samuel Cos Corral
    Pages 171-181
  9. Melatonin and Malaria: Therapeutic Avenues

    • Venkataramanujam Srinivasan, Mahaneem Mohamed, Rahimah Zakaria, Asma Hayati Ahmad, Rozieyati Mohamed Saleh
    Pages 183-192
  10. Melatonin’s Role in Human Reproduction: Recent Studies

    • Rahimah Zakaria, Amnon Brzezinski, Venkataramanujam Srinivasan
    Pages 193-203
  11. Melatonin and Pain: Therapeutic Applications

    • Venkataramanujam Srinivasan, Khek-Yu Ho, Dario Acuña-Castroviejo, Rahimah Zakaria, Amnon Brzezinski, Edward C. Lauterbach
    Pages 221-234
  12. Melatonin in Alzheimer’s Disease: Focus on Neuroprotective Role

    • Venkataramanujam Srinivasan, Edward C. Lauterbach, Charanjit Kaur, Asma Hayati Ahmad, Mahaneem Mohamed, Atul Prasad et al.
    Pages 235-247
  13. Melatonin in Parkinson’s Disease and Its Therapeutic Potential

    • Venkataramanujam Srinivasan, U. S. Srinivasan, Charanjit Kaur, Rahimah Zakaria, Zahiruddin Othman, Edward C. Lauterbach et al.
    Pages 249-261
  14. Melatonin and Its Agonists in Sleep Disorders

    • Amnon Brzezinski
    Pages 263-273
  15. Agomelatine in Depressive Disorders

    • Sidney H. Kennedy, Franca M. Placenza
    Pages 275-279

About this book

 

The book aims to cover basic physiologic functions of melatonin, and its therapeutic applications in humans for a variety of clinically relevant disorders. This book contains chapters on the recent aspects of melatonin physiology, its receptors and their role in mitochondrial function, its immunomodulatory role and importance in seasonal dependent diseases, role in human reproduction, role in sleep, circadian rhythm and sleep disorders, role in neurologic disorders such as Parkinson’s disease, Alzheimer’s disease. Additionally, melatonin’s therapeutic use in neurobehavioral disorders in children, migraine and tension headache is also covered in this book. Melatonin’s antioxidant role in Duchenne’s muscular dystrophy and in glaucoma have also been discussed in short chapters. Two major melatonin agonists, ramelteon and agomelatine are discussed extensively on their current clinical application and ongoing research. Two chapters on agomelatonin and its role in mood disorders, particularly depressive disorders, are an important feature of this book. The chapters are written by experts from the global academia recognized for their original research and published work in the field of melatonin science.

Reviews

From the book reviews:

“A review in 29 chapters of the various proven or possible effects of melatonin on physiological states and diseases. The controversial issues of clinical and therapeutic applications are backed up by many references. For those interested in the possible use of Melatonin in sleep and neurological disorders.” (Pediatric Endocrinology Reviews (PER), Vol. 12 (1), September, 2014)

“This book reviews melatonin and its therapeutic clinical application in human disorders. … The book is aimed at a wide audience including students, neurologists, psychiatrists, psychopharmacologists, oncologists, and scientists with an interest in melatonin. … It would be helpful for those in a variety of disciplines, including students, researchers, and clinicians.” (M. Isabel L. Crisostomo, Doody’s Book Reviews, June, 2014)

Editors and Affiliations

  • Sri Sathya Sai Medical Educational and Research Foundation, An International Medical Sciences Research Center, Coimbatore, India

    V. Srinivasan

  • Department of Obstetrics and Gynecology, Hadassah Hebrew-University Medical Center, Jerusalem, Israel

    Amnon Brzezinski

  • Department of Physiology, Gulhane Military Medical Academy, Ankara, Turkey

    Sukru Oter

  • Department of Psychiatry Behavioral Sciences, Mercer University School of Medicine, Macon, Georgia, USA

    Samuel D. Shillcutt

About the editors

V.Srinivasan Ph.D MAMS
Sri Sathya Sai Medical Educational and Research Foundation
An International Medical Sciences Research Foundation
Prasanthi Nilayam, 40-Kovai Thirunagar, Goldwins, KOVAI
Coimbatore-641014, Tamilnadu, INDIA

Bibliographic Information

  • Book Title: Melatonin and Melatonergic Drugs in Clinical Practice

  • Editors: V. Srinivasan, Amnon Brzezinski, Sukru Oter, Samuel D. Shillcutt

  • DOI: https://doi.org/10.1007/978-81-322-0825-9

  • Publisher: Springer New Delhi

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer India 2014

  • Hardcover ISBN: 978-81-322-0824-2Published: 27 January 2014

  • Softcover ISBN: 978-81-322-2854-7Published: 23 August 2016

  • eBook ISBN: 978-81-322-0825-9Published: 10 January 2014

  • Edition Number: 1

  • Number of Pages: XVII, 402

  • Number of Illustrations: 27 b/w illustrations, 19 illustrations in colour

  • Topics: Internal Medicine, Endocrinology, Psychiatry, Psychopharmacology, Neurology, Oncology

Buy it now

Buying options

eBook USD 89.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 119.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access