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Major Histocompatibility Complex

Evolution, Structure, and Function

Editors: Kasahara, M. (Ed.)

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  • ISBN 978-4-431-65868-9
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Hardcover $139.99
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About this book

Every biological system is the outcome of evolution and has a history all its own. This history dictates how the system works and why it has certain properties and not others. This is why we need to study not only the structure and function, but also the history of the system. This argument undoubtedly applies to the study of the immune system and also to the study of the major histocompatibility complex (MHC). Since 1989, researchers of various scientific disciplines who share a deep inter­ est in MHC evolution have held a meeting every two years to discuss their latest research developments, exchange ideas, and foster friendship. Together with my colleagues Drs. Naoyuki Takahata and Yoko Satta, I organized the Sixth Interna­ tional Workshop on MHC Evolution in Hayama, Japan, May 25-29, 1999. This volume is the proceedings of that conference. It covers diverse topics pertinent to MHC evolution, including the origin of the adaptive immune system, the organi­ zation of the MHC in humans and other model vertebrates, MHC-parasite co­ evolution, and the nature and origin of MHC polymorphism. I hope that this book will be of interest not only for MHC researchers and immunologists, but also for other specialists who are interested in the evolution of biological systems in gen­ eral.

Table of contents (39 chapters)

Table of contents (39 chapters)
  • Jaws and AIS

    Pages 3-26

    Klein, Jan (et al.)

  • The MHC paralogous group: listing of members and a brief overview

    Pages 27-44

    Kasahara, Masanori (et al.)

  • The MHC « Big-Bang » : duplication and exon shuffling during chordate evolution. A hypothetico-deductive approach

    Pages 45-52

    Rached, Laurent Abi (et al.)

  • Relationships among the genes encoding MHC molecules and the specific antigen receptors

    Pages 53-65

    Pasquier, Louis

  • Conserved linkage among sea urchin homologs of genes encoded in the vertebrate MHC region

    Pages 66-74

    Rast, Jonathan P. (et al.)

Buy this book

eBook $109.00
price for USA in USD (gross)
  • ISBN 978-4-431-65868-9
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $139.99
price for USA in USD
  • ISBN 978-4-431-70276-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $139.99
price for USA in USD
  • ISBN 978-4-431-65870-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Major Histocompatibility Complex
Book Subtitle
Evolution, Structure, and Function
Editors
  • M. Kasahara
Copyright
2000
Publisher
Springer Japan
Copyright Holder
Springer Japan
eBook ISBN
978-4-431-65868-9
DOI
10.1007/978-4-431-65868-9
Hardcover ISBN
978-4-431-70276-4
Softcover ISBN
978-4-431-65870-2
Edition Number
1
Number of Pages
XXIII, 561
Number of Illustrations
86 b/w illustrations, 4 illustrations in colour
Topics