Skin Permeation and Disposition of Therapeutic and Cosmeceutical Compounds

Editors: Sugibayashi, Kenji (Ed.)

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  • Presents a general introduction to skin permeation and disposition of chemical compounds in the first part to review the basic study as well as the R&D on topical and transdermal drug delivery systems and cosmetics
  • Provides comments from dermatologists and pharmacists, which are especially useful for R&D in the industry
  • Discusses safety assessment of topically applied compounds, which only a few books pay attention to
  • Contains many contributions by Japanese and other Asian academics and researchers
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eBook $189.00
price for USA in USD (gross)
  • ISBN 978-4-431-56526-0
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $249.99
price for USA in USD
  • ISBN 978-4-431-56524-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $249.99
price for USA in USD
  • Customers within the U.S. and Canada please contact Customer Service at +1-800-777-4643, Latin America please contact us at +1-212-460-1500 (24 hours a day, 7 days a week).
  • Due: January 26, 2020
  • ISBN 978-4-431-56812-4
  • Free shipping for individuals worldwide
About this book

This book reviews skin permeation and disposition of chemical compounds. Skin is utilized as an administration site for transdermal drug delivery systems, topical drug formulations, cosmeceuticals, and cosmetics. Their usefulness is closely related to the permeation and disposition of entrapped active ingredients through and into the skin. Skin permeation, disposition, and metabolism of chemicals are first summarized in the general introduction. Then primary topical formulations are explained in the second part, “Basic Formulations Applied to Skin”. The explanation for the active compounds and formulations are of the most important parts required to fabricate these formulations. Skin absorption of chemicals is generally much lower than oral and the other mucosal absorptions, so that skin-penetration enhancement is a key issue to have good formulations topically applied. Part 3 presents “Skin Penetration Enhancement”. In addition, Part 4, “Selection of Topically Applied Chemical Candidates”, deals with selection methods of topically applied ingredients for transdermal drug delivery systems, topical drug formulations, cosmeceuticals, and cosmetics. Parts 5 and 6, “Safety Assessment of Topically Applied Compounds“ and “Experimental Methods of Skin Permeation“, respectively, show safety issues and experimental methods for topical formulations. The final part consists of comments on therapeutic and cosmetic formulations by medical doctors and pharmacists. Their comments are especially helpful for pharmaceutical and cosmetic researchers who study dermatopharmacokinetics and topical formulations.

This volume is particularly useful for those working in R&D, graduate students, and educators in the area of pharmaceutics, cosmetic sciences, dermatological sciences, pharmacology, toxicology, biopharmacy, pharmacokinetics, physical pharmacy, chemical engineering, and related fields.

About the authors

Kenji Sugibayashi, Ph.D.

President,

Josai International University

and

Professor,

Graduate School of Pharmaceutical Sciences and Faculty of Pharmacy and Pharmaceutical Sciences, Josai University

Reviews

“This book can be useful for graduate students and people working in the area of pharmaceutical and cosmetic research and industrial settings. It also can serve as a reference for graduate teaching of topics related to skin biology, skin toxicology, transdermal drug delivery, and other related fields. … This book covers in detail important topics in skin biology and toxicology … .” (Tiangang Li, Doody's Book Reviews, May, 2018)

Table of contents (39 chapters)

Table of contents (39 chapters)
  • Skin Morphology and Permeation Pathway Through the Skin

    Sugibayashi, Kenji

    Pages 3-11

  • Skin Permeation of Chemicals

    Sugibayashi, Kenji

    Pages 13-53

  • Chemical Disposition in Skin

    Sugibayashi, Kenji

    Pages 55-65

  • Skin Metabolism of Chemicals

    Hatanaka, Tomomi

    Pages 67-76

  • Systematic Absorption of Chemicals and Their Kinetics

    Hatanaka, Tomomi

    Pages 77-85

Buy this book

eBook $189.00
price for USA in USD (gross)
  • ISBN 978-4-431-56526-0
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $249.99
price for USA in USD
  • ISBN 978-4-431-56524-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $249.99
price for USA in USD
  • Customers within the U.S. and Canada please contact Customer Service at +1-800-777-4643, Latin America please contact us at +1-212-460-1500 (24 hours a day, 7 days a week).
  • Due: January 26, 2020
  • ISBN 978-4-431-56812-4
  • Free shipping for individuals worldwide
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Bibliographic Information

Bibliographic Information
Book Title
Skin Permeation and Disposition of Therapeutic and Cosmeceutical Compounds
Editors
  • Kenji Sugibayashi
Copyright
2017
Publisher
Springer Japan
Copyright Holder
Springer Japan KK
eBook ISBN
978-4-431-56526-0
DOI
10.1007/978-4-431-56526-0
Hardcover ISBN
978-4-431-56524-6
Softcover ISBN
978-4-431-56812-4
Edition Number
1
Number of Pages
X, 428
Number of Illustrations
75 b/w illustrations, 78 illustrations in colour
Topics