Overview
Presents up-to-date coverage of a rapidly developing field
Integrates information across distinct model systems, encompassing invertebrate and vertebrate brain
Written by leading experts in the field
Describes the wide range of research on dendrites in health and in disease
Contrasts development and degeneration
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Table of contents (22 chapters)
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Front Matter
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Introduction
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Front Matter
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Basic Biology of Dendrites
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Front Matter
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Patterning Dendritic Architecture of Neurons and Their Populations
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Front Matter
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Cellular and Molecular Control of Dendrite Development and Maintenance
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Front Matter
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Synapse Formation Onto Dendrites
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Front Matter
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Keywords
About this book
Studies in human patients and animal models of disease suggest a strong correlation between defects in dendrite development and common neurological disorders such as autism. Much of this book is thus dedicated toward highlighting recent advances in our understanding of the cellular and molecular mechanisms that regulate the development and maintenance of dendrites, a crucial component of neurons. The book begins by presenting the current state of knowledge on the building blocks or cell biology of dendrites. Mechanisms that sculpt the stereotypic architecture of dendritic arbors and shape their connectivity are also discussed, along with recent work describing how dendritic organization and connectivity are perturbed in disease. A unique aspect of the book is its exploration of diverse neuronal cell types across vertebrates and invertebrates, allowing a comparison of mechanisms across distinct circuits and species. The book comprises six parts, which cover the major advances in the field: Part 1, Introduction; Part 2, Basic Biology of Dendrites; Part 3, Patterning Dendritic Architecture of Neurons and Their Populations; Part 4, Cellular and Molecular Control of Dendrite Development and Maintenance; Part 5, Synapse Formation onto Dendrites; and Part 6, Dendrites in Disease. The book offers an excellent point of entry for students interested in neuroscience, as well as for clinicians.
Editors and Affiliations
About the editors
Kazuo Emoto: Professor, Department of Biological Sciences, The University of Tokyo, Japan
Rachel Wong: Professor, Department of Structural Biology, University of Washington, USA
Eric Huang: Professor, Department of Pathology, University of California San Francisco, USA
Casper Hoogenraad: Professor, Department of Biology, Utrecht University, The Netherlands
Bibliographic Information
Book Title: Dendrites
Book Subtitle: Development and Disease
Editors: Kazuo Emoto, Rachel Wong, Eric Huang, Casper Hoogenraad
DOI: https://doi.org/10.1007/978-4-431-56050-0
Publisher: Springer Tokyo
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer Japan 2016
Hardcover ISBN: 978-4-431-56048-7Published: 30 August 2016
Softcover ISBN: 978-4-431-56764-6Published: 22 April 2018
eBook ISBN: 978-4-431-56050-0Published: 19 August 2016
Edition Number: 1
Number of Pages: VII, 608
Number of Illustrations: 18 b/w illustrations, 86 illustrations in colour
Topics: Neurosciences, Neurology, Animal Models