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Dendrites

Development and Disease

Editors: Emoto, K., Wong, R., Huang, E., Hoogenraad, C. (Eds.)

  • Presents up-to-date coverage of a rapidly developing field
  • Integrates information across distinct model systems, encompassing invertebrate and vertebrate brain
  • Written by leading experts in the field
  • Describes the wide range of research on dendrites in health and in disease
  • Contrasts development and degeneration
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eBook $189.00
price for USA in USD (gross)
  • ISBN 978-4-431-56050-0
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $249.99
price for USA in USD
  • ISBN 978-4-431-56048-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $249.99
price for USA in USD
  • ISBN 978-4-431-56764-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

Studies in human patients and animal models of disease suggest a strong correlation between defects in dendrite development and common neurological disorders such as autism. Much of this book is thus dedicated toward highlighting recent advances in our understanding of the cellular and molecular mechanisms that regulate the development and maintenance of dendrites, a crucial component of neurons. The book begins by presenting the current state of knowledge on the building blocks or cell biology of dendrites. Mechanisms that sculpt the stereotypic architecture of dendritic arbors and shape their connectivity are also discussed, along with recent work describing how dendritic organization and connectivity are perturbed in disease. A unique aspect of the book is its exploration of diverse neuronal cell types across vertebrates and invertebrates, allowing a comparison of mechanisms across distinct circuits and species. The book comprises six parts, which cover the major advances in the field: Part 1, Introduction; Part 2, Basic Biology of Dendrites; Part 3, Patterning Dendritic Architecture of Neurons and Their Populations; Part 4, Cellular and Molecular Control of Dendrite Development and Maintenance; Part 5, Synapse Formation onto Dendrites; and Part 6, Dendrites in Disease. The book offers an excellent point of entry for students interested in neuroscience, as well as for clinicians.

About the authors

Kazuo Emoto: Professor, Department of Biological Sciences, The University of Tokyo, Japan

Rachel Wong: Professor, Department of Structural Biology, University of Washington, USA

Eric Huang: Professor, Department of Pathology, University of California San Francisco, USA

Casper Hoogenraad: Professor, Department of Biology, Utrecht University, The Netherlands

Table of contents (22 chapters)

  • Introduction

    Emoto, Kazuo (et al.)

    Pages 3-6

  • Cytoskeletal Organization: Actin

    Abou Elezz, Amr (et al.)

    Pages 9-29

  • Microtubule Organization and Microtubule-Associated Proteins (MAPs)

    Tortosa, Elena (et al.)

    Pages 31-75

  • Membrane Trafficking Mechanisms: Exocytosis and Endocytosis in Dendrites

    Winckler, Bettina, Ph.D.

    Pages 77-109

  • Activity Dependent Protein Transport from the Synapse to the Nucleus

    Bera, Sujoy (et al.)

    Pages 111-124

Buy this book

eBook $189.00
price for USA in USD (gross)
  • ISBN 978-4-431-56050-0
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $249.99
price for USA in USD
  • ISBN 978-4-431-56048-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $249.99
price for USA in USD
  • ISBN 978-4-431-56764-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Dendrites
Book Subtitle
Development and Disease
Editors
  • Kazuo Emoto
  • Rachel Wong
  • Eric Huang
  • Casper Hoogenraad
Copyright
2016
Publisher
Springer Japan
Copyright Holder
Springer Japan
eBook ISBN
978-4-431-56050-0
DOI
10.1007/978-4-431-56050-0
Hardcover ISBN
978-4-431-56048-7
Softcover ISBN
978-4-431-56764-6
Edition Number
1
Number of Pages
VII, 608
Number of Illustrations
18 b/w illustrations, 86 illustrations in colour
Topics