Pathogenesis and Treatment in IgA Nephropathy

An International Comparison

Editors: Tomino, Yasuhiko (Ed.)

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  • Presents an international comparison of the pathogenesis and treatment of IgA nephropathy
  • Covers genetic variation, aberrant IgA1 production, and classification etiology, guidelines, and treatment goals
  • Forms an essential reference for the clinician who deals with this disease and also for the researcher who would like to learn about recent treatments in this field
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eBook $149.00
price for USA in USD (gross)
  • ISBN 978-4-431-55588-9
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  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $199.99
price for USA in USD
  • ISBN 978-4-431-55587-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $199.99
price for USA in USD
  • ISBN 978-4-431-56664-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

This book discusses the latest findings on the pathogenesis and treatment of IgA nephropathy. It particularly focuses on recently recognized initiation and progression factors and the varying treatment strategies in different regions, such as Asia, Europe, and the United States. More than 40 years have passed since Dr. Jean Berger first described primary IgA nephropathy (“Nephropathy with mesangial IgA-IgG deposits”) as a new disease entity.

Immunohistopathologically, IgA nephropathy is characterized by the granular deposition of IgA (IgA1) and C3 in the glomerular mesangial areas with mesangial cell proliferation and the expansion of mesangial matrices. It is clear that IgA nephropathy is one of the most common types of chronic glomerulonephritis in the world. This disease may lead to end-stage kidney disease, with its enormous economic impact on healthcare everywhere. Efforts by many investigators around the world have gradually clarified various aspects of the pathogenesis and treatment of IgA nephropathy. However, there are many controversial strategies for the treatment of patients with IgA nephropathy throughout the world, as there are several limitations for treatment in each country. This volume provides nephrologists everywhere with an overview and comparison of both global and regional findings in basic and clinical fields in IgA nephropathy. It covers genetic variation, aberrant IgA1 production, and classification etiology, guidelines, and treatment goals, with all chapters written by top international researchers.

About the authors

Editor: Dr. Yasuhiko Tomino
Division of Nephropathy, Department of Internal Medicine, Juntendo University Faculty of Medicine, Tokyo, Japan
(Present address: Medical Corporation SHOWAKAI, Tokyo, Japan)

Reviews

“This is an informative look at IgA nephropathy, one of the most common types of chronic glomerulonephritis in the world. … This is a resource for those engaged in research or clinical care of patients with IgA nephropathy. It is likely most appropriate for nephrology trainees and those who practice general nephrology, as well as researchers in the field. … Each chapter is divided into sections, clearly demarcated by objectives, and includes colorful images and figures.” (Jon Webb, Doody's Book Reviews, February, 2017)


Table of contents (20 chapters)

Table of contents (20 chapters)
  • Is IgA Nephropathy a Single Disease?

    Cheung, Chee Kay (et al.)

    Pages 3-17

  • Advances in Genetics of Immunoglobulin A Nephropathy

    Zhang, Hong (et al.)

    Pages 19-42

  • Is IgA Nephropathy (IgAN) a Familial or Sporadic Disease?

    Narita, Ichiei (et al.)

    Pages 43-51

  • Heterogeneity of Aberrant O-Glycosylation of IgA1 in IgA Nephropathy

    Novak, Jan (et al.)

    Pages 53-68

  • Differences of Histological Classification Between the Japanese Histological Grade Classification and the Oxford Classification

    Joh, Kensuke (et al.)

    Pages 69-87

Buy this book

eBook $149.00
price for USA in USD (gross)
  • ISBN 978-4-431-55588-9
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $199.99
price for USA in USD
  • ISBN 978-4-431-55587-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $199.99
price for USA in USD
  • ISBN 978-4-431-56664-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Pathogenesis and Treatment in IgA Nephropathy
Book Subtitle
An International Comparison
Editors
  • Yasuhiko Tomino
Copyright
2016
Publisher
Springer Japan
Copyright Holder
Springer Japan
eBook ISBN
978-4-431-55588-9
DOI
10.1007/978-4-431-55588-9
Hardcover ISBN
978-4-431-55587-2
Softcover ISBN
978-4-431-56664-9
Edition Number
1
Number of Pages
XI, 342
Number of Illustrations
36 b/w illustrations, 10 illustrations in colour
Topics