Overview
Covers the multiple physiological/pathological functions of semaphorins beyond one research field
Reviews the recent studies by leading scientists in the field
Helps the reader to understand the general concept of semaphorins, which consist of more than 20 family members
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Table of contents (11 chapters)
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Front Matter
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Back Matter
Keywords
About this book
This book presents the current concepts of semaphorin biology. In the early 1990s, semaphorins were originally identified as axon guidance cues that function during neuronal development. However, cumulative findings have clarified that they have diverse functions in many physiological processes, including cardiogenesis, angiogenesis, vasculogenesis, osteoclastogenesis, retinal homeostasis, and immune regulation. Additionally, they have been implicated in the pathogenesis of various human diseases, including tumorigenesis/tumor metastasis, neuroregenerative diseases, retinal degeneration, irregular pulse/sudden death, and immune disorders. Based on this current research background, the book covers the essential state-of-the-art findings for basic scientists in biochemistry, molecular biology, neuroscience, developmental biology, and structural biology, as well as for physicians in neurology, cardiology, oncology, orthopedic surgery, otorhinolaryngology, ophthalmology, allergology, and rheumatology.
Editors and Affiliations
Bibliographic Information
Book Title: Semaphorins
Book Subtitle: A Diversity of Emerging Physiological and Pathological Activities
Editors: Atsushi Kumanogoh
DOI: https://doi.org/10.1007/978-4-431-54385-5
Publisher: Springer Tokyo
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer Japan 2015
Hardcover ISBN: 978-4-431-54384-8Published: 20 May 2015
Softcover ISBN: 978-4-431-56349-5Published: 29 October 2016
eBook ISBN: 978-4-431-54385-5Published: 07 May 2015
Edition Number: 1
Number of Pages: VIII, 226
Number of Illustrations: 2 b/w illustrations, 46 illustrations in colour
Topics: Immunology, Neurobiology, Cancer Research, Cell Biology, Angiology, Molecular Medicine