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Birkhäuser

Chemokine Biology: Basic Research and Clinical Application

  • Book
  • © 2007

Overview

  • Comprehensive and up-to-date overview of the field
  • Both volumes complement each other, but can also be used independently from each other
  • Written by leading experts in the field
  • The volume editors organized several international conferences on chemokines

Part of the book series: Progress in Inflammation Research (PIR)

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Keywords

  • Animal disease models
  • Cell biology
  • Drug targets
  • Homeostasis

About this book

Chemokines play an important role in recruiting inflammatory cells into tissues in response to infection and inflammation. They also play an important role in coordinating the movement of T-cells, B-cells and dentritic cells, necessary to generate an immune response (response to injury, allergens, antigens, invading microorganisms). They selectively attract leukocytes to inflammatory foci, inducing both cell migration and activation. They are involved in various diseases, like atherosclerosis, lung and skin inflammation, multiple sclerosis, or HIV. Volume 1 of this two-volume set discusses the immunobiology of chemokines. It is divided into two parts: a) cellular targets in innate and adaptive immunity, and b) effector cell traffic-unrelated functions. Together with volume 2, which discusses the pathophysiology of chemokines, both volumes give a comprehensive overview of chemokine biology.

Editors and Affiliations

  • Bone and Inflammation, Eli Lilly and Company Lilly Corporate Center, Indianapolis, USA

    Kuldeep Neote

  • Universität Bern Inst. für Zellbiologie, Bern, Switzerland

    Bernhard Moser

Bibliographic Information

  • Book Title: Chemokine Biology: Basic Research and Clinical Application

  • Editors: Gordon L. Letts, Kuldeep Neote, Bernhard Moser

  • Series Title: Progress in Inflammation Research

  • Publisher: Birkhäuser Basel

  • Copyright Information: Birkhäuser Basel 2007

  • Series ISSN: 1422-7746

  • Series E-ISSN: 2296-4525

  • Edition Number: 1

  • Number of Pages: 224

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