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Progress in Inflammation Research

Chemokine Biology - Basic Research and Clinical Application

Vol. 2: Pathophysiology of Chemokines

Editors: Neote, Kuldeep, Letts, L. Gordon, Moser, Bernhard (Eds.)

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  • Comprehensive and up-to-date overview of the field
  • Both volumes complement each other, but can also be used independently from each other
  • Written by leading experts in the field
  • The volume editors organized several international conferences on chemokines
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About this book

Chemokines play an important role in recruiting inflammatory cells into tissues in response to infection and inflammation. They also play an important role in coordinating the movement of T-cells, B-cells and dentritic cells, necessary to generate an immune response (response to injury, allergens, antigens, invading microorganisms). They selectively attract leukocytes to inflammatory foci, inducing both cell migration and activation. They are involved in various diseases, like atherosclerosis, lung and skin inflammation, multiple sclerosis, or HIV.
Volume 2 of this two-volume set discusses the pathophysiology of chemokines. It is divided into two parts: a) chemokines in animal disease models, and b) chemokines as drug targets. Together with volume 1, which discusses the immunobiology of chemokines, both volumes give a comprehensive overview of chemokine biology.

Table of contents (11 chapters)

Table of contents (11 chapters)
  • Chemokines in animal models of inflammation

    Pages 3-17

    Kunkel, Steven L. (et al.)

  • Autoimmune diseases

    Pages 19-26

    Karpus, William J.

  • Chemokines in allergic responses: eosinophils, basophils, mast cells

    Pages 27-41

    Mikhak, Zamaneh (et al.)

  • Chemokines as drug targets

    Pages 45-59

    Proudfoot, Amanda E. I. (et al.)

  • Screening and characterization of cyclic pentapeptide CXCR4 antagonists/inverse agonists using a pheromone responsive reporter gene in Saccharomyces cerevisiae: Utility of G protein coupled receptor constitutively active mutants

    Pages 61-77

    Wang, Zi-xuan (et al.)

Buy this book

eBook $139.00
price for USA in USD
  • ISBN 978-3-7643-7437-2
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $179.99
price for USA in USD
  • ISBN 978-3-7643-7195-1
  • Free shipping for individuals worldwide
  • Immediate ebook access, if available*, with your print order
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Chemokine Biology - Basic Research and Clinical Application
Book Subtitle
Vol. 2: Pathophysiology of Chemokines
Editors
  • Kuldeep Neote
  • L. Gordon Letts
  • Bernhard Moser
Series Title
Progress in Inflammation Research
Copyright
2007
Publisher
Birkhäuser Basel
Copyright Holder
Birkhäuser Basel
eBook ISBN
978-3-7643-7437-2
DOI
10.1007/978-3-7643-7437-2
Hardcover ISBN
978-3-7643-7195-1
Series ISSN
0379-0363
Edition Number
1
Number of Pages
XII, 171
Topics

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