Progress in Inflammation Research

Regulatory T Cells in Inflammation

Editors: Taams, Leonie S., Akbar, Arne N., Wauben, Marca H.M. (Eds.)

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About this book

Regulatory T-cells are essential components of the immune system, and several different subsets of regulatory T-cells have been described. Considerable regulatory function has been attributed to the CD4+CD25+ T-cell subset. These cells act by suppressing adaptive and possibly innate immune responses thereby maintaining or restoring the balance between immunity and tolerance. The suppressive effects of CD4+CD25+ regulatory T-cells are cell-contact dependent.

Recent developments and viewpoints in the field of CD4+CD25+ regulatory T-cells as well as the potential use of regulatory T-cells in immunotherapy of inflammatory diseases are discussed in this volume. By linking data from experimental models with recent findings from the clinic, this book will be of interest to immunologists and other biomedical researchers as well as clinicians interested in the regulation and manipulation of the immune response during inflammatory disease.

Table of contents (12 chapters)

Table of contents (12 chapters)
  • History of CD25+CD4+ regulatory T cells

    Sakaguchi, Shimon (et al.)

    Pages 3-17

  • “Natural” and “induced” regulatory T cells — purpose and problems associated with an emerging distinction

    Homann, Dirk (et al.)

    Pages 19-38

  • The role of interleukin-10 in regulatory-T-cell suppression: reconciling the discrepancies

    Barker, Robert N. (et al.)

    Pages 39-61

  • Activation and distribution of regulatory T cells in naïve and antigen-stimulated immune systems

    Nolte-’t Hoen, Esther N.M. (et al.)

    Pages 63-75

  • Regulatory T cells and the innate immune system

    Maloy, Kevin J. (et al.)

    Pages 77-91

Buy this book

eBook $199.00
price for USA in USD (gross)
  • ISBN 978-3-7643-7301-6
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $259.00
price for USA in USD
  • ISBN 978-3-7643-7088-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Regulatory T Cells in Inflammation
Editors
  • Leonie S. Taams
  • Arne N. Akbar
  • Marca H.M. Wauben
Series Title
Progress in Inflammation Research
Copyright
2005
Publisher
Birkhäuser Basel
Copyright Holder
Birkhäuser Basel
eBook ISBN
978-3-7643-7301-6
DOI
10.1007/b137037
Hardcover ISBN
978-3-7643-7088-6
Series ISSN
0379-0363
Edition Number
1
Number of Pages
XI, 240
Topics