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Polymer and Cell Dynamics

Multiscale Modelling and Numerical Simulations

  • Book
  • © 2003

Overview

Editors:
  1. Wolfgang Alt

    1. Abteilung Theoretische Biologie Botanisches Institut, Universität Bonn, Bonn, Germany

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  2. Mark Chaplain

    1. Department of Mathematics, University of Dundee, Dundee, UK

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  3. Michael Griebel

    1. Institut für Angewandte Mathematik (IAM) Abteilung Wissenschaftliches Rechnen und Numerische Simulation, Universität Bonn, Bonn, Germany

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  4. Jürgen Lenz

    1. Bioreact GmbH, Botanisches Institut, Bonn, Germany

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  • New results on mathematical modeling and computer simulation
  • Critical evaluation of theoretical methods, their advantages and limitations
  • Interdisciplinary approach
  • Mathematical and numerical methods and relevant applications
  • Close connection with experimental practice

Part of the book series: Mathematics and Biosciences in Interaction (MBI)

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Table of contents (20 chapters)

  1. Front Matter

    Pages i-xii
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  2. Molecular Dynamics and Protein Configuration

    1. Front Matter

      Pages 1-1
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    2. Introduction to Part I

      • Wolfgang Alt, Mark Chaplain, Michael Griebel, Jürgen Lenz
      Pages 3-5

    3. Molecular Dynamics Studies of Micelle and Capsid Self-assembly

      • Dennis C. Rapaport
      Pages 7-17

    4. A Functional Study on Saposin B and C Using Experimentally Validated Models

      • Daniel Hoffmann
      Pages 19-27

    5. A Review of the Morph Server and the Macromolecular Motions Database: A Standardized System for Analyzing and Visualizing Macromolecular Motions in a Database Framework

      • Werner G. Krebs, Mark Gerstein
      Pages 29-42

  3. Polymer Dynamics and Cell Motility

    1. Front Matter

      Pages 43-43
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    2. Introduction to Part II

      • Wolfgang Alt, Mark Chaplain, Michael Griebel, Jürgen Lenz
      Pages 45-48

    3. Brownian Dynamics of Flexible Polymers in Flow

      • Roland Rzehak, Andreas Arend, Diego Kienle, Walter Zimmermann
      Pages 49-68

    4. A Microscopic Model for the Dynamics of Actin Filaments in Motility Assays and its Numerical Simulation

      • Zénó Farkas, Imre Derényi, Tamás Vicsek
      Pages 69-74

    5. Multiparticle Modeling of Actin-Myosin Networks: From Molecular Interactions to Cell Motility

      • Jürgen Lenz, Dieter Felix
      Pages 75-89

    6. Analysis of Cell Motility Combining Cytomechanical Model Simulations and an Optical Flow Method

      • Angélique Stéphanou, Xavier Ronot, Philippe Tracqui
      Pages 91-112

    7. Micropipet Aspiration of the Human Neutrophil

      • Jeanie L. Drury, Micah Dembo
      Pages 113-124

    8. Physical-object-oriented 3D Simulations of Cell Deformations and Migration

      • Emmanuel Promayon, Jean-Louis Martiel, Philippe Tracqui
      Pages 125-138

  4. Multicellular Dynamics

    1. Front Matter

      Pages 139-139
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    2. Introduction to Part III

      • Wolfgang Alt, Mark Chaplain, Michael Griebel, Jürgen Lenz
      Pages 141-144

    3. Computational Modeling of Blood Clotting: Coagulation and Three-dimensional Platelet Aggregation

      • Aaron Fogelson, Haoyu Yu, Andrew Kuharsky
      Pages 145-154

    4. Space- and Time-resolved Simulations of Processes in Biofilm Systems on a Microscale

      • Hans-Joachim Bungartz, Martin Kühn, Miriam Mehl, Stefan Würtz
      Pages 155-167

    5. On Selected Individual-based Approaches to the Dynamics in Multicellular Systems

      • Dirk Drasdo
      Pages 169-203

    6. Individual-based Models of Cohort Migration in Cell Cultures

      • András Czirók, Andreas Deutsch, Michael Wurzel
      Pages 205-219
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Keywords

About this book

Polymer and cell dynamics play an important role in processes like tumor growth, metastasis, embryogenesis, immune reactions and regeneration. This volume – based on an international workshop on numerical simulations of polymer and cell dynamics in Bad Honnef (Germany) in 2000 – provides an overview of the relevant mathematical and numerical methods, their applications and limits. The contributions are from the fields of applied and numerical mathematics, scientific computing, theoretical physics, molecular biophysics, cell and molecular biology as well as chemical and biomedical engineering. The volume will be of interest to scientists and advanced undergraduates in the fields of biotechnology, biomedicine, applied mathematics, biomathematics, biophysics and bioinformatics.

Editors and Affiliations

  • Abteilung Theoretische Biologie Botanisches Institut, Universität Bonn, Bonn, Germany

    Wolfgang Alt

  • Department of Mathematics, University of Dundee, Dundee, UK

    Mark Chaplain

  • Institut für Angewandte Mathematik (IAM) Abteilung Wissenschaftliches Rechnen und Numerische Simulation, Universität Bonn, Bonn, Germany

    Michael Griebel

  • Bioreact GmbH, Botanisches Institut, Bonn, Germany

    Jürgen Lenz

Bibliographic Information

  • Book Title: Polymer and Cell Dynamics

  • Book Subtitle: Multiscale Modelling and Numerical Simulations

  • Editors: Wolfgang Alt, Mark Chaplain, Michael Griebel, Jürgen Lenz

  • Series Title: Mathematics and Biosciences in Interaction

  • DOI: https://doi.org/10.1007/978-3-0348-8043-5

  • Publisher: Birkhäuser Basel

  • eBook Packages: Springer Book Archive

  • Copyright Information: Birkhäuser Verlag Basel, Switzerland 2003

  • Hardcover ISBN: 978-3-7643-6924-8Published: 25 August 2003

  • Softcover ISBN: 978-3-0348-9417-3Published: 12 November 2012

  • eBook ISBN: 978-3-0348-8043-5Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: XII, 308

  • Topics: Mathematical and Computational Biology, Simulation and Modeling

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