Overview
First comprehensive overview to the topic
Introduces new concepts in therapeutical treatment
With contributions of international experts
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Table of contents (10 chapters)
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General Properties of T-Type Ca2+ Channels
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Role of T-Type Ca2+ Channels in Disease
Keywords
About this book
T-type calcium channels are prevalent in every organ of the body, and are believed to play a part in a variety of physiological processes, including contraction, shape change, secretion, endo- and exocytosis, cell proliferation and differentiation, modulation of enzyme function, and cell cycle progression. As such, research on the roles of these channels in a wide range of diseases has attracted increasing attention in recent years. The purpose of this book is to present a series of unique and comprehensive reviews of our current understanding of T-type calcium channels at the level of the basic sciences as well as the clinical sciences. For key organ systems, information is provided on the correlation between the molecular, biophysical and pharmacological properties of the channels, their cellular mechanisms, and their potential roles in the pathogenesis of various diseases. The compilation presents both commonplace and less well-known findings on these channels in a format designed to appeal to both casual readers and specialists in basic and clinical research on these transporters.​
Editors and Affiliations
Bibliographic Information
Book Title: T-type Calcium Channels in Basic and Clinical Science
Editors: Stephen W. Schaffer, Ming Li
DOI: https://doi.org/10.1007/978-3-7091-1413-1
Publisher: Springer Vienna
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer-Verlag Wien 2015
Hardcover ISBN: 978-3-7091-1412-4Published: 12 December 2014
Softcover ISBN: 978-3-7091-1954-9Published: 23 August 2016
eBook ISBN: 978-3-7091-1413-1Published: 26 November 2014
Edition Number: 1
Number of Pages: X, 154
Number of Illustrations: 11 b/w illustrations, 6 illustrations in colour
Topics: Molecular Medicine, Cell Biology, Human Physiology