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Handbook of Experimental Pharmacology

Pain Control

Editors: Schaible, Hans-Georg (Ed.)

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  • Highlights key mechanisms of pain generation and pain chronification
  • Addresses emerging novel concepts and targets for pain therapy 
  • Addresses novel peripheral, spinal and cerebral targets for pain therapy 
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eBook $269.00
price for USA in USD (gross)
  • ISBN 978-3-662-46450-2
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $349.99
price for USA in USD
  • ISBN 978-3-662-46449-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $349.99
price for USA in USD
  • Customers within the U.S. and Canada please contact Customer Service at +1-800-777-4643, Latin America please contact us at +1-212-460-1500 (24 hours a day, 7 days a week).
  • Due: November 18, 2016
  • ISBN 978-3-662-51357-6
  • Free shipping for individuals worldwide
About this book

This volume addresses neuronal pain mechanisms at the peripheral, spinal and supraspinal level which are thought to significantly contribute to pain and which may be the basis for the development of new treatment principles. Chapters on nociceptive mechanisms in the peripheral nociceptive system address the concept of hyperalgesic priming, the role of voltage-gated sodium channels in different inflammatory and neuropathic pain states, the hyperalgesic effects of NGF in different tissues and in inflammatory and neuropathic pain states, and the contribution of proteinase activated receptors (PAR) to the development of pain in several chronic pain conditions. Chapters on nociceptive mechanisms in the spinal cord address the particular role of NO and of glial cell activation in the generation and maintenance of inflammatory and neuropathic pain and it discusses the potential role of local inhibitory interneurons, of the endogenous endocannabinoid system and the importance of non-neuronal immune mechanisms in opioid signaling in the control of pain. Furthermore, it is presented how spinal mechanisms contribute to the expression of peripheral inflammation.

Table of contents (14 chapters)

Table of contents (14 chapters)

Buy this book

eBook $269.00
price for USA in USD (gross)
  • ISBN 978-3-662-46450-2
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $349.99
price for USA in USD
  • ISBN 978-3-662-46449-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $349.99
price for USA in USD
  • Customers within the U.S. and Canada please contact Customer Service at +1-800-777-4643, Latin America please contact us at +1-212-460-1500 (24 hours a day, 7 days a week).
  • Due: November 18, 2016
  • ISBN 978-3-662-51357-6
  • Free shipping for individuals worldwide
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Bibliographic Information

Bibliographic Information
Book Title
Pain Control
Editors
  • Hans-Georg Schaible
Series Title
Handbook of Experimental Pharmacology
Series Volume
227
Copyright
2015
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-662-46450-2
DOI
10.1007/978-3-662-46450-2
Hardcover ISBN
978-3-662-46449-6
Softcover ISBN
978-3-662-51357-6
Series ISSN
0171-2004
Edition Number
1
Number of Pages
VIII, 309
Number of Illustrations
9 b/w illustrations, 22 illustrations in colour
Topics