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Apoptosis: Mechanisms and Role in Disease

  • Book
  • © 1998

Overview

Editors:
  1. Sharad Kumar

    1. Hanson Centre for Cancer Research, Institute of Medical and Veterinary Science, Adelaide, Australia

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  • This book gives a broad overview of apoptosis, with particular reference to its mechanisms and role in diseases

Part of the book series: Results and Problems in Cell Differentiation (RESULTS, volume 24)

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Table of contents (11 chapters)

  1. Front Matter

    Pages I-XIII
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  2. Caspases in Cell Death

    • Loretta Dorstyn, Makoto Kinoshita, Sharad Kumar
    Pages 1-24

  3. Proteolytic Targets in Cell Death

    • Dianne Watters, Nigel Waterhouse
    Pages 25-44

  4. The Point of No Return: Mitochondria, Caspases, and the Commitment to Cell Death

    • Douglas R. Green, Gustavo P. Amarante-Mendes
    Pages 45-61

  5. Serpins and Regulation of Cell Death

    • Phillip I. Bird
    Pages 63-89

  6. The IAP Family of Apoptotic Regulators

    • Lisa J. Eiben, Colin S. Duckett
    Pages 91-104

  7. Apoptosis Versus Necrosis: The Shape of Neuronal Cell Death

    • Marcel Leist, Pierluigi Nicotera
    Pages 105-135

  8. Prevention of Neuronal Cell Death by Bcl-2

    • Yoshihide Tsujimoto
    Pages 137-155

  9. CD95 (APO-1/Fas) in Hematopoietic Diseases

    • Klaus-Michael Debatin
    Pages 157-174

  10. The Cornified Envelope: A Model of Cell Death in the Skin

    • Gerry Melino, Vincenzo De Laurenzi, M. Valeria Catani, Alessandro Terrinoni, Barbara Ciani, Eleonora Candi et al.
    Pages 175-212

  11. Radiation-Induced Cell Death and its Implications in Human Disease

    • Martin F. Lavin
    Pages 213-232

  12. T Cell Apoptosis in HIV Infection: Mechanisms and Relevance for AIDS Pathogenesis

    • Marie-Lise Gougeon, Eric Ledru, Hervé Lecoeur, Sylvie Garcia
    Pages 233-248

  13. Back Matter

    Pages 249-256
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Keywords

About this book

The past few years have seen rapid progress in apoptosis research. This volume deals with many of the recent advances made in uncovering the molecular and cellular basis of apoptosis and elaborates on how this accumulating knowledge is helping us to understand the significance of apoptosis in pathogenesis of diseases arising from inappropriate cell death. Further, mechanistic aspects of cell death and role of apoptosis in disease is covered.
The articles published in this volume are written by leading experts in the field and should be a vital resource for researchers in biomedicine and cancer research.

Editors and Affiliations

  • Hanson Centre for Cancer Research, Institute of Medical and Veterinary Science, Adelaide, Australia

    Sharad Kumar

Bibliographic Information

  • Book Title: Apoptosis: Mechanisms and Role in Disease

  • Editors: Sharad Kumar

  • Series Title: Results and Problems in Cell Differentiation

  • DOI: https://doi.org/10.1007/978-3-540-69185-3

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 1998

  • Softcover ISBN: 978-3-662-21625-5Published: 13 November 2013

  • eBook ISBN: 978-3-540-69185-3Published: 11 November 2013

  • Series ISSN: 0080-1844

  • Series E-ISSN: 1861-0412

  • Edition Number: 1

  • Number of Pages: XIII, 255

  • Number of Illustrations: 50 b/w illustrations

  • Topics: Cell Biology, Biochemistry, general, Cancer Research

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