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Mitochondrial DNA Mutations in Aging, Disease and Cancer

Editors: Singh, Keshav K. (Ed.)

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  • Most comprehensive, up-to-date analysis of the role of mitochondria in aging and diseases.

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eBook $119.00
price for USA in USD (gross)
  • ISBN 978-3-662-12509-0
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Softcover $159.99
price for USA in USD
  • ISBN 978-3-662-12511-3
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  • Usually dispatched within 3 to 5 business days.
About this book

Many human genetic diseases associated with blood, brain, colon, ear, eye, heart, kidney, liver, muscle, and pancreas are caused by mutations in mitochondrial DNA. Mutations in DNA can result in defects of the electron transport complexes, intermediates of the tricarboxylic acid cycle and substrate transport. The clinical manifestation of these diseases often involves muscle and the nervous system. Mitochondrial DNA mutations have now been associated with aging as well as age-related degenerative diseases such as Parkinson's, Alzheimer's, and Huntington's diseases. Changes in structure, function, and a number of mitochondria play an important role in carcinogenesis. Furthermore, the role of mitochondria in the execution of programmed cell death or apoptosis has been recognized recently.

Table of contents (20 chapters)

Table of contents (20 chapters)

Buy this book

eBook $119.00
price for USA in USD (gross)
  • ISBN 978-3-662-12509-0
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $159.99
price for USA in USD
  • ISBN 978-3-662-12511-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Mitochondrial DNA Mutations in Aging, Disease and Cancer
Editors
  • Keshav K. Singh
Copyright
1998
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-662-12509-0
DOI
10.1007/978-3-662-12509-0
Softcover ISBN
978-3-662-12511-3
Edition Number
1
Number of Pages
XX, 412
Number of Illustrations
42 b/w illustrations, 6 illustrations in colour
Additional Information
Jointly published with Landes Bioscience, Georgetown, USA
Topics