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  • © 1997

Intracellular Antibodies

Development and Applications

  • This is the first book to describe how antibodies can be exploited to block biological functions or to confer new phenotypic traits (e.g. resistance to a virus).

Part of the book series: Biotechnology Intelligence Unit (BIOIU)

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Table of contents (11 chapters)

  1. Front Matter

    Pages i-xiii
  2. Intracellular and Intercellular Immunization

    • Antonino Cattaneo, Silvia Biocca
    Pages 1-7
  3. Recombinant Antibodies for Ectopic Expression

    • Andrew Bradbury
    Pages 15-39
  4. Protein Sequence Motifs Involved in Intracellular Trafficking

    • Silvia Biocca, Antonino Cattaneo
    Pages 59-83
  5. Intercellular Immunization

    • Antonino Cattaneo, Patrizia Piccioli, Francesca Ruberti
    Pages 85-104
  6. Intracellular Immunization

    • Silvia Biocca, Antonino Cattaneo
    Pages 105-124
  7. Plantibodies: Immunomodulation and Immunotherapeutic Potential

    • Rosella Franconi, Paraskevi Tavladoraki, Eugenio Benvenuto
    Pages 145-171
  8. From Phage Libraries to Intracellular Immunization

    • Nicola Gargano, Luisa Fasulo, Silvia Biocca, Antonino Cattaneo
    Pages 173-186
  9. Perspectives and Conclusions

    • Antonino Cattaneo, Silvia Biocca
    Pages 187-189
  10. Back Matter

    Pages 191-196

About this book

Recent advances in the field of recombinant antibodies have permitted the manipulation of genes encoding specific antibodies, thus allowing their ectopic expression in a wide variety of non-lymphoid cells. This volume describes how the ectopic expression of antibodies, as secreted or as intracellularly retargeted molecules, can be exploited to block biological functions or to confer new phenotypic traits (e.g. resistance to a virus). This is the first book describing this emerging technology, which is receiving increasing attention for application in many different fields and biological systems - from human gene therapy to plant biotechnology.

Editors and Affiliations

  • Biophysics Sector, International School for Advanced Studies (SISSA), Trieste, Italy

    Antonino Cattaneo

  • Department of Experimental Medicine and Biochemical Sciences, University of Rome “Tor Vergata”, Roma, Italy

    Silvia Biocca

Bibliographic Information

  • Book Title: Intracellular Antibodies

  • Book Subtitle: Development and Applications

  • Editors: Antonino Cattaneo, Silvia Biocca

  • Series Title: Biotechnology Intelligence Unit

  • DOI: https://doi.org/10.1007/978-3-662-07992-8

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 1997

  • Softcover ISBN: 978-3-662-07994-2Published: 03 December 2012

  • eBook ISBN: 978-3-662-07992-8Published: 09 March 2013

  • Edition Number: 1

  • Number of Pages: XIII, 196

  • Number of Illustrations: 20 b/w illustrations

  • Additional Information: Jointly published with Landes Bioscience, Georgetown, USA

  • Topics: Cell Biology, Immunology, Biotechnology, Molecular Medicine

Buy it now

Buying options

eBook USD 39.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access