Ernst Schering Foundation Symposium Proceedings

Of Fish, Fly, Worm, and Man

Lessons from Developmental Biology for Human Gene Function and Disease

Editors: Nüsslein-Volhard, C., Krätzschmar, J. (Eds.)

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About this book

The first complete genome sequence of a multicellular organism, Caenorhabditis elegans, has been determined recently. Several more will follow soon, among them the genome sequences of Drosophila melanogaster and the human. With these achievements, the stage is set for the next phase of "large-scale" biology, the study of the function of genes and the interactions between their protein products. The aim of the Ernst Schering Research Foundation Workshop 29 was to discuss the contribution of research on model organisms which are particularly suited for genetic and biological research, to the understanding of gen­ eral principles of biology as well as the basis for human diseases. This area of research has not only unveiled the basic molecular mechanisms of development of higher organisms, but has also made major contri­ butions to the elucidation of complex signal transduction pathways that play crucial roles both in ontogeny and human diseases. Establishing the complete molecular anatomy of an organism is a demanding but rather well-defined task. However, compared to the technical and scientific challenges of large-scale sequencing and the bioinformatics analysis of complete genome data, the assignment of function to the genes of multicellular organisms may still seem like a fishing expedition, with no universal road to success. One approach is based on large-scale technologies. The use of mi­ croarrays for multiple gene expression analysis is one element in this effort, providing important information on the cell- or tissue-specific activation of genes over time.

Table of contents (12 chapters)

Table of contents (12 chapters)

Buy this book

eBook $84.99
price for USA in USD
  • ISBN 978-3-662-04264-9
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $109.00
price for USA in USD
  • ISBN 978-3-662-04266-3
  • Free shipping for individuals worldwide
  • Institutional customers should get in touch with their account manager
  • Shipping restrictions
  • Usually ready to be dispatched within 3 to 5 business days, if in stock
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Bibliographic Information

Bibliographic Information
Book Title
Of Fish, Fly, Worm, and Man
Book Subtitle
Lessons from Developmental Biology for Human Gene Function and Disease
Editors
  • C. Nüsslein-Volhard
  • J. Krätzschmar
Series Title
Ernst Schering Foundation Symposium Proceedings
Series Volume
29
Copyright
2000
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-662-04264-9
DOI
10.1007/978-3-662-04264-9
Softcover ISBN
978-3-662-04266-3
Series ISSN
0947-6075
Edition Number
1
Number of Pages
XV, 243
Number of Illustrations
83 b/w illustrations
Topics