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Alzheimer’s Disease

Etiological Mechanisms and Therapeutic Possibilities

  • Conference proceedings
  • © 1996

Overview

Editors:
  1. J. D. Turner

    1. Neuropsychopharmacology, Schering AG, Berlin, Germany

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  2. K. Beyreuther

    1. Center for Molecular Biology, University of Heidelberg, Heidelberg, Germany

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    You can also search for this editor in PubMed   Google Scholar

  3. F. Theuring

    1. Institute of Cellular and Molecular Biology, Schering AG, Berlin, Germany

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Part of the book series: Ernst Schering Foundation Symposium Proceedings (SCHERING FOUND, volume 17)

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Table of contents (11 papers)

  1. Front Matter

    Pages I-XIII
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  2. Alzheimer’s Disease With and Without Familial Aggregation: A Case for Phenotypical Similarity

    • O. Almkvist, V. Jelic, L. Lannfelt, A. Nordberg, M. Shigeta, L.-O. Wahlund et al.
    Pages 1-15

  3. The Vascular Dementias and Cerebrovascular Involvement in Alzheimer’s Disease

    • J. G. Schulz, K. M. Einhäupl
    Pages 17-48

  4. The Genes Involved in Alzheimer’s Disease

    • J. Hardy, M. Hutton
    Pages 49-59

  5. In Vivo Biology of Amyloid Precursor Protein/Amyloid Precursor-like Proteins and Transgenic Animal Models of Alzheimer’s Disease

    • S. S. Sisodia, G. Thinakaran, B. T. Lamb, H. H. Slunt, C. S. von Koch, S. D. Ginsberg et al.
    Pages 61-76

  6. Molecular Processing Pathways of β-Amyloid Precursor Protein: Therapeutic Implications

    • C. Haass
    Pages 77-92

  7. Regulation of Amyloid β-Protein Precursor Processing by Cell Surface Receptor Ligands and Second Messengers

    • R. M. Nitsch
    Pages 93-107

  8. Tau Phosphorylation and Dephosphorylation in the Pathogenesis of Alzheimer’s Disease

    • M. Mawal-Dewan, J. Q. Trojanowski, V. M.-Y. Lee
    Pages 109-126

  9. Cytokines in Alzheimer’s and Other Neurodegenerative Diseases

    • N. J. Rothwell
    Pages 127-146

  10. Inflammation in the CNS and in Alzheimer’s Disease

    • V. H. Perry, M. D. Bell, D. Anthony
    Pages 147-168

  11. Protein Modifications and Interactions in Alzheimer’s Disease

    • M. A. Smith, G. Perry
    Pages 169-182

  12. Protein Aging and Its Relevance to the Etiology of Alzheimer’s Disease

    • E. R. Stadtman
    Pages 183-208

  13. Back Matter

    Pages 209-213
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Keywords

About this book

Alzheimer's Disease is a progressive neurodegenerative disorder of late life with devastating consequences for the afflicted and their carers and poses one of the major challenges to medical research. Until recently, little hope of effective therapies capable of slowing the disease process or preventing its occurrence was apparent. With recent advances in the genetics and molecular biology of the disease processes and the demonstration of the involvement of multiple aetiological factors, however, real chances are now appearing for the identification of preventive drugs. In this discussion, experts from disciplines ranging from molecular genetics to the clinic provide review and novel data concerning the aetiology of AD and the establishment of drugfinding screening methods.

Editors and Affiliations

  • Neuropsychopharmacology, Schering AG, Berlin, Germany

    J. D. Turner

  • Center for Molecular Biology, University of Heidelberg, Heidelberg, Germany

    K. Beyreuther

  • Institute of Cellular and Molecular Biology, Schering AG, Berlin, Germany

    F. Theuring

Bibliographic Information

  • Book Title: Alzheimer’s Disease

  • Book Subtitle: Etiological Mechanisms and Therapeutic Possibilities

  • Editors: J. D. Turner, K. Beyreuther, F. Theuring

  • Series Title: Ernst Schering Foundation Symposium Proceedings

  • DOI: https://doi.org/10.1007/978-3-662-03248-0

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 1996

  • Softcover ISBN: 978-3-662-03250-3Published: 12 December 2012

  • eBook ISBN: 978-3-662-03248-0Published: 14 March 2013

  • Series ISSN: 0947-6075

  • Edition Number: 1

  • Number of Pages: XIII, 216

  • Number of Illustrations: 11 b/w illustrations

  • Topics: Neurology, Clinical Psychology, Pharmaceutical Sciences/Technology

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