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Magnetic Resonance of Myelin, Myelination, and Myelin Disorders

  • Book
  • © 1989

Overview

Authors:
  1. Jacob Valk

    1. Department of Diagnostic Radiology and Neuroradiology, Free University Hospital, Amsterdam, The Netherlands

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  2. Marjo S. Knaap

    1. Department of Child Neurology, Academic Hospital, Utrecht, The Netherlands

    View author publications

    You can also search for this author in PubMed   Google Scholar

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Table of contents (52 chapters)

  1. Front Matter

    Pages I-XVIII
    Download chapter PDF

  2. Introduction

    • Jacob Valk, Marjo S. van der Knaap
    Pages 1-3

  3. Classification of Myelin Disorders

    • Jacob Valk, Marjo S. van der Knaap
    Pages 4-8

  4. White Matter and Myelin

    • Jacob Valk, Marjo S. van der Knaap
    Pages 9-21

  5. Basic Principles of Magnetic Resonance Imaging and its Application in Myelin Disorders

    • Jacob Valk, Marjo S. van der Knaap
    Pages 22-25

  6. Myelination and Retarded Myelination

    • Jacob Valk, Marjo S. van der Knaap
    Pages 26-65

  7. Lysosomes and Lysosomal Disorders

    • Jacob Valk, Marjo S. van der Knaap
    Pages 66-67

  8. Metachromatic Leukodystrophy

    • Jacob Valk, Marjo S. van der Knaap
    Pages 68-76

  9. Globoid Cell Leukodystrophy: Krabbe’s Disease

    • Jacob Valk, Marjo S. van der Knaap
    Pages 77-82

  10. Wolman’s Disease and Cholesterol Ester Storage Disease

    • Jacob Valk, Marjo S. van der Knaap
    Pages 83-84

  11. Niemann-Pick Disease

    • Jacob Valk, Marjo S. van der Knaap
    Pages 85-87

  12. GM1 Gangliosidosis

    • Jacob Valk, Marjo S. van der Knaap
    Pages 88-90

  13. GM2 Gangliosidosis

    • Jacob Valk, Marjo S. van der Knaap
    Pages 91-94

  14. Fucosidosis

    • Jacob Valk, Marjo S. van der Knaap
    Pages 95-96

  15. Peroxisomes and Peroxisomal Disorders

    • Jacob Valk, Marjo S. van der Knaap
    Pages 97-98

  16. Zellweger Cerebrohepatorenal Syndrome

    • Jacob Valk, Marjo S. van der Knaap
    Pages 99-103

  17. Adrenoleukodystrophy

    • Jacob Valk, Marjo S. van der Knaap
    Pages 104-112

  18. Refsum’s Disease

    • Jacob Valk, Marjo S. van der Knaap
    Pages 113-118

  19. Hyperpipecolic Acidemia

    • Jacob Valk, Marjo S. van der Knaap
    Pages 119-120

  20. Pseudo-Zellweger Syndrome

    • Jacob Valk, Marjo S. van der Knaap
    Pages 121-121
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Keywords

About this book

Magnetic resonance imaging (MRI) is now considered the imaging modality of choice for the majority of disorders affecting the central nervous system. This is particularly true for gray and white matter disorders, thanks to the superb soft tis­ sue contrast in MRI which allows gray matter, unmyelinated, and myelinated white matter to be distinguished and their respective disorders identified. The pre­ sent book is devoted to the disorders of myelin and myelination. A growing amount of detailed in vivo information about myelin, myelination, and myelin dis­ orders has been derived both from MRI and from MR spectroscopy (MRS). This prompted us to review the clinical, laboratory, biochemical, and pathological data on this subject in order to integrate all available information and to provide im­ proved insights into normal and disordered myelin and myelination. We will show how the synthesis of all available information contributes to the interpretation of MR images. After a brief historical review about the increasing knowledge on myelin and my­ elin disorders, we propose a new classification of myelin disorders based on the subcellular localization of the enzymatic defects as far as the inborn errors of me­ tabolism are concerned. This classification serves as a guide throughout the book. All items of the classification will be discussed and, whenever relevant and possi­ ble, be illustrated by MR images.

Authors and Affiliations

  • Department of Diagnostic Radiology and Neuroradiology, Free University Hospital, Amsterdam, The Netherlands

    Jacob Valk

  • Department of Child Neurology, Academic Hospital, Utrecht, The Netherlands

    Marjo S. Knaap

Bibliographic Information

  • Book Title: Magnetic Resonance of Myelin, Myelination, and Myelin Disorders

  • Authors: Jacob Valk, Marjo S. Knaap

  • DOI: https://doi.org/10.1007/978-3-662-02568-0

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 1989

  • eBook ISBN: 978-3-662-02568-0Published: 17 April 2013

  • Edition Number: 1

  • Number of Pages: XVIII, 390

  • Topics: Neuroradiology, Neurology

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