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International Symposium on Adriamycin

Milan, 9th-10th September, 1971

  • Conference proceedings
  • © 1972

Overview

Editors:
  1. Stephen K. Carter

    1. Chief Cancer Therapy Evaluation Branch National Cancer Institute, Bethesda, USA

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  2. A. Di Marco

    1. National Cancer Institute, Milan, Italy

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  3. M. Ghione

    1. Chief, Medical Research Farmitalia, Milan, Italy

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  4. I. H. Krakoff

    1. Sloan Kettering Institute for Cancer Research, New York, USA

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  5. G. Mathé

    1. Institut de Cancérologie et d’Immunogénétique, Villejuif, France

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Table of contents (35 papers)

  1. Front Matter

    Pages I-VIII
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  2. Short Summary of the Informal Meeting Preceeding the Adriamycin Symposium

    1. Short Summary of the Informal Meeting Preceeding the Adriamycin Symposium

      • Stephen K. Carter, A. Di Marco, M. Ghione, I. H. Krakoff, G. Mathé
      Pages 1-7

  3. Chemistry of Adriamycin

    1. Front Matter

      Pages 9-9
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    2. Structure and Physicochemical Properties of Adriamycin (Doxorubicin)

      • F. Arcamone, G. Cassinelli, G. Franceschi, S. Penco, C. Pol, S. Redaelli et al.
      Pages 9-22

  6. Pharmacology and Pharmacokinetics

    1. Front Matter

      Pages 96-96
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    2. Influence of Pharmacokinetic Variations on the Pharmacological Properties of Adriamycin

      • E. Arena, N. D’Alessandro, L. Dusonchet, N. Gebbia, F. Gerbasi, R. Sanguedolce et al.
      Pages 96-116

    3. Pharmacokinetics and Metabolism of Adriamycin and Daunomycin

      • D. W. Yesair, M. A. Asbell, R. Bruni, F. J. Bullock, E. Schwartzbach
      Pages 117-123

    4. Blood Levels, Tissue Distribution and Clinical Effects of Adriamycin

      • Kiyoji Kimura, Hiroshi Fujita, Yasunobu Sakai
      Pages 124-134

  7. Clinical Activity and Side Effects

    1. Front Matter

      Pages 135-135
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    2. Adriamycin in the Treatment of Acute Leukemia

      • H. Begemann, G. Wernekke
      Pages 135-138
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Keywords

About this book

The impressive advances in all branches of medical science during the first half of this century with the discovery of many chemotherapeutic or immunogenic agents gave rise to brilliant achievements in the struggle against some infectious diseases and aroused in many scientists the wishful thought that drugs for cancer therapy would, soon lead to additional great success. Notwithstanding ever-increasing worldwide endeavors, the major problems in prevention or treatment of neoplastic diseases are still unsolved. The approach to the resolution of these problems follows many different pathways. Basic research tries to cast light on the genetic and biochemical processes underly­ ing cell division and differentiation as well as the interactions occurring between the cell and the oncogenic stimulus, or between the neoplastic cells and the different body systems endowed with immunological reactivity. Another line of approach, coherent with the classic basis of chemotherapy, relies upon the search for new compounds selectively blocking the multiplication of the neoplastic cells. The remarkable progress made in treating human cancer, as a result of these efforts, has been until now ascribable chiefly to the accomplishment of the chemo­ therapeutic approach. Studies on the cytostatic activity of the anthracycline antibiotics carried out over many years eventually led the investigators of Farmitalia (Milan, Italy) to discover and characterize some new compounds endowed with interesting chemotherapeutic properties against malignant neoplastic diseases.

Editors and Affiliations

  • Chief Cancer Therapy Evaluation Branch National Cancer Institute, Bethesda, USA

    Stephen K. Carter

  • National Cancer Institute, Milan, Italy

    A. Di Marco

  • Chief, Medical Research Farmitalia, Milan, Italy

    M. Ghione

  • Sloan Kettering Institute for Cancer Research, New York, USA

    I. H. Krakoff

  • Institut de Cancérologie et d’Immunogénétique, Villejuif, France

    G. Mathé

Bibliographic Information

  • Book Title: International Symposium on Adriamycin

  • Book Subtitle: Milan, 9th-10th September, 1971

  • Editors: Stephen K. Carter, A. Di Marco, M. Ghione, I. H. Krakoff, G. Mathé

  • DOI: https://doi.org/10.1007/978-3-642-95227-2

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag, Berlin · Heidelberg 1972

  • Softcover ISBN: 978-3-642-95229-6Published: 12 February 2012

  • eBook ISBN: 978-3-642-95227-2Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: VIII, 252

  • Topics: Pharmacology/Toxicology, Medicine/Public Health, general

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