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Immunology of Silicones

  • Conference proceedings
  • © 1996

Overview

Editors:
  1. Michael Potter

    1. Laboratory of Genetics, National Cancer Institute, National Institutes of Health, Bethesda, USA

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  2. Noel R. Rose

    1. Departments of Pathology and of Molecular Microbiology and Immunology, John Hopkins University, Baltimore, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Current Topics in Microbiology and Immunology (CT MICROBIOLOGY, volume 210)

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Table of contents (46 papers)

  1. Front Matter

    Pages I-XX
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  2. Silicon, Silica, Silicones: Chemistry and Degradation

    1. Front Matter

      Pages 1-1
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    2. Silica, Silicon and Silicones...Unraveling the Mystery

      • T. H. Lane, S. A. Burns
      Pages 3-12

    3. Silicone Degradation Reactions

      • Chris Batich, Don DePalma, James Marotta, Guy Latorre
      Pages 13-23

    4. Chemical, Physical and Mechanical Analysis of Explanted Breast Implants

      • C. J. Wolf, H. J. Brandon, V. L. Young, K. L. Jerina, A. P. Srivastava
      Pages 25-37

    5. Silicon and Silicone Levels in Patients with Silicone Implants

      • W. Peters, D. Smith, S. Lugowski, A. McHugh, P. MacDonald, C. Baines
      Pages 39-48

    6. Detection of Silicone Migration and Biodegradation with NMR

      • L. Garrido, A. Bogdanova, L. L. Cheng, B. Pfleiderer, E. Tokareva, J. L. Ackerman et al.
      Pages 49-58

    7. Serum Silicon Levels are Elevated in Women with Silicone Gel Implants

      • S. S. Teuber, R. L. Saunders, G. M. Halpern, R. F. Brucker, V. Conte, B. D. Goldman et al.
      Pages 59-65

  3. Interaction of Silicones with Proteins and Tissues

    1. Front Matter

      Pages 67-67
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    2. The Development of an ELISA Method for the Detection of “Antibodies” to Silicone

      • B. Rosenau, A. B. Schneebaun, P. H. Schur
      Pages 69-74

    3. The Adsorption of Proteins on a Polydimethylsiloxane Elastomer (PEP) and Their Antigenic Behavior

      • J. E. Butler, E. P. Lü, P. Navarro, B. Christiansen
      Pages 75-84

    4. Aspecific Immunoglobulin Binding to Hydrophobic Surfaces

      • C. J. van Oss, J. O. Naim
      Pages 85-91

    5. Cytotoxicity and Membrane Damage in vitro by Inclusion Complexes Between γ-Cyclodextrin and Siloxanes

      • K. Felix, S. Janz, J. Pitha, J. A. Williams, E. B. Mushinski, G. W. Bornkamm et al.
      Pages 93-99

  4. Adjuvancy of Silicones

    1. Front Matter

      Pages 101-101
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    2. Induction of Type II Collagen Arthritis in the DA Rat Using Silicone Gel as Adjuvant

      • J. O. Naim, K. M. L. Ippolito, R. J. Lanzafame, C. J. van Oss
      Pages 103-111

    3. The Adjuvancy of Silicones: Dependency on Compartmentalization

      • P. C. Klykken, K. L. White Jr.
      Pages 113-121

    4. The Adjuvant Effect of Silicone Gel and Silicone Elastomer Particles in Rats

      • S. L. Hill, M. G. Landavere, N. R. Rose
      Pages 123-137

    5. Silicone Gel and Octamethylcyclotetrasiloxane Potentiate Antibody Production to Bovine Serum Albumin in Mice

      • J. J. Nicholson III, G. E. Wong, C. G. Frondoza, N. R. Rose
      Pages 139-144

  5. Macrophages, Polyreactive and Antilipid Antibodies

    1. Front Matter

      Pages 145-145
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    2. Fibrogenic and Other Biological Effects of Silica

      • Anthony C. Allison
      Pages 147-158
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Keywords

About this book

This issue of Current Topics in Microbiology and Immunology records the proceedings of a Workshop on the Immunology of Sili­ cones held at the Natcher Conference Center, National Institutes of Health, Bethesda, Maryland, March 13 and 14, 1995. A large num­ ber of investigators from North America and Europe met to discuss available data on how the immune system responds to silicones and related materials. Some aspects of this field are controversial. Nonetheless, the meeting was marked by a civil and open ex­ change of scientific information and divergent interpretations, re­ flecting the traditions of scientific communication. Each invited participant was asked to submit an article sum­ marizing his/her presentation. Most of the papers are published as submitted, with only editorial changes to conform with the guide­ lines given to each contributor or revisions to clarify aspects of the paper. The papers should not be regarded as peer-reviewed publi­ cations. This preface will attempt to outline some of the immu­ nological areas of investigation relating to silicones.

Editors and Affiliations

  • Laboratory of Genetics, National Cancer Institute, National Institutes of Health, Bethesda, USA

    Michael Potter

  • Departments of Pathology and of Molecular Microbiology and Immunology, John Hopkins University, Baltimore, USA

    Noel R. Rose

Bibliographic Information

  • Book Title: Immunology of Silicones

  • Editors: Michael Potter, Noel R. Rose

  • Series Title: Current Topics in Microbiology and Immunology

  • DOI: https://doi.org/10.1007/978-3-642-85226-8

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE, part of Springer Nature 1996

  • Softcover ISBN: 978-3-642-85228-2Published: 09 February 2012

  • eBook ISBN: 978-3-642-85226-8Published: 06 December 2012

  • Series ISSN: 0070-217X

  • Series E-ISSN: 2196-9965

  • Edition Number: 1

  • Number of Pages: XX, 430

  • Number of Illustrations: 28 b/w illustrations

  • Topics: Immunology, Oncology, Rheumatology

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