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Recent Results in Cancer Research

Familial and Hereditary Tumors

Authors: Ponz de Leon, Maurizio

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About this book

For many years the etiology of human tumors has almost exclusively been attributed to environmental factors, which seemed to be involved not only in the induction of neo­ plasms but also in other phases of tumorigenesis. Cigarette smoking and alcohol are the two best known examples of factors related to our modern lifestyle which have been implicated in the development of cancer of various organs. From the 1960s onward, the pioneer work of a few investigators clearly showed that hereditary factors were not only related to rare neoplasms, but could also be respon­ sible for the occurrence of a sizeable fraction of tumors that do not usually show features of inheritance (as in the case of breast or colorectal cancer). Thus, the idea that some common human malignancies could be transmitted from one generation to another with features of mendelian gene­ tics became more and more evident. In addition, the verit­ able explosion of molecular biology in the last 15 years has made a further and substantial contribution to the emerging role of genetics in biomedical research and particularly in cancer.

Table of contents (22 chapters)

  • Introduction

    Leon, Prof. Dr. M. Ponz

    Pages 1-8

  • Genetic Aspects of Diseases: Categories of Genetic Disorders

    Leon, Prof. Dr. M. Ponz

    Pages 9-23

  • Biomarkers of Increased Susceptibility to Cancer

    Leon, Prof. Dr. M. Ponz

    Pages 24-34

  • Oncogenes and Tumor Suppressor Genes

    Leon, Prof. Dr. M. Ponz

    Pages 35-47

  • Genetic Factors in Solid Tumors of Childhood

    Leon, Prof. Dr. M. Ponz

    Pages 48-58

Buy this book

eBook $119.00
price for USA in USD (gross)
  • ISBN 978-3-642-85076-9
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $159.00
price for USA in USD
  • ISBN 978-3-642-85078-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Familial and Hereditary Tumors
Authors
Series Title
Recent Results in Cancer Research
Series Volume
136
Copyright
1994
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-642-85076-9
DOI
10.1007/978-3-642-85076-9
Softcover ISBN
978-3-642-85078-3
Series ISSN
0080-0015
Edition Number
1
Number of Pages
X, 349
Number of Illustrations and Tables
7 b/w illustrations
Topics