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Nato ASI Subseries H:

Cancer Therapy

Differentiation, Immunomodulation and Angiogenesis

Editors: D'Alessandro, N., Mihich, E., Rausa, L., Tapiero, H., Tritton, Th.R. (Eds.)

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eBook $119.00
price for USA in USD (gross)
  • ISBN 978-3-642-84613-7
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $159.00
price for USA in USD
  • ISBN 978-3-642-84615-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

Provided here is a comprehensive examination of the basic and clinical condition of three innovative and promising approaches to cancer therapy, which may support or even substitute chemotherapy: differentiation, immunomodulation, and inhibition of angiogenesis. Differentiation shouldnormalize neoplastic cells and make them compatible with the host. Its feasibility with retinoids, interferons, chemotherapeutic and other agents is discussed. Modulation by biological agents, cytotoxic effector cells and drugs is considered in attempts to boost endogenous antitumour defenses and/or to render neoplastic cells more susceptible to the immune attack of the host. Finally, the important aspect of interfering with tumour blood vessel development and function is taken into account. Consideringthe importance that chemotherapy has in cancer treatment and in view of a more and more integrated strategy, the relationship between the aforementioned approaches and chemotherapeutic agents and chemoresistance is treated in detail.

Table of contents (24 chapters)

  • Colon Cancer Cell Differentiation as Related to Methotrexate and 5-Fluorouracil Resistance

    Zweibaum, A. (et al.)

    Pages 1-15

  • The Control of Cell Multiplication and Differentiation in Human Myelomonocytic Cells

    Huberman, E. (et al.)

    Pages 17-32

  • Signal Transduction Through the Epstein-Barr Virus Receptor in Human B Lymphocytes

    Frade, R.

    Pages 33-38

  • Signal Transduction Mechanisms as a Target for Cancer Chemotherapy

    Tritton, Thomas R.

    Pages 39-49

  • Therapeutic Approaches for Colon Cancer Based on Transcriptional Regulation of Specific Growth Factors

    Brattain, M. G. (et al.)

    Pages 51-69

Buy this book

eBook $119.00
price for USA in USD (gross)
  • ISBN 978-3-642-84613-7
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $159.00
price for USA in USD
  • ISBN 978-3-642-84615-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Cancer Therapy
Book Subtitle
Differentiation, Immunomodulation and Angiogenesis
Editors
  • Natale D'Alessandro
  • Enrico Mihich
  • Luciano Rausa
  • Haim Tapiero
  • Thomas R. Tritton
Series Title
Nato ASI Subseries H:
Series Volume
75
Copyright
1993
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-642-84613-7
DOI
10.1007/978-3-642-84613-7
Softcover ISBN
978-3-642-84615-1
Series ISSN
1010-8793
Edition Number
1
Number of Pages
XI, 288
Topics