Springer Series in Synergetics

Theories of Immune Networks

Editors: Atlan, Henri, Cohen, Irun R. (Eds.)

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For a long time, immunology has been dominated by the idea of a simple linear cause-effect relationship between the exposure to an antigen and the production of specific antibodies against that antigen. Clonal selection was the name of the theory based on this idea and it has provided the main concepts to account for the known features of the immune response. More recently, immunologists have discovered a wealth of new facts, in the form of different regulatory cells (helpers, suppressors, antigen presenting cells), genetic determinations of immune responses such as those involved in graft re­ jections, different molecular structures responsible for intercellular interactions such as interleukins, cytokins, idiotype-antiidiotype recognition and others. While furthering our understanding of the local interactions (molecular and cellular) in­ volved in the immune response, these discoveries have led to a questioning of the simplicities of the classical clonal selection theory. It is clear today that every single immune response is a cooperative phenomenon involving several different molecular and cellular interactions taking place in a coupled manner. In addition, cross reactivity to different antigens has shown that responses of the whole im­ mune system to different antigens are not completely isolated from one another and that the history of encounters with different antigens plays a crucial role in the maturation of the whole system. Thus, problems of complexity, generation of di­ versity and self-organization have entered the field of immunology.

Table of contents (11 chapters)

Table of contents (11 chapters)

Buy this book

eBook $119.00
price for USA in USD (gross)
  • ISBN 978-3-642-83935-1
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $159.99
price for USA in USD
  • ISBN 978-3-642-83937-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Theories of Immune Networks
Editors
  • Henri Atlan
  • Irun R. Cohen
Series Title
Springer Series in Synergetics
Series Volume
46
Copyright
1989
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-642-83935-1
DOI
10.1007/978-3-642-83935-1
Softcover ISBN
978-3-642-83937-5
Series ISSN
0172-7389
Edition Number
1
Number of Pages
VIII, 117
Topics