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Triiodothyronines in Health and Disease

  • Book
  • © 1981

Overview

Authors:
  1. Inder J. Chopra

    1. Center for the Health Sciences, UCLA School of Medicine, Los Angeles, USA

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Part of the book series: Monographs on Endocrinology (ENDOCRINOLOGY, volume 18)

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Table of contents (9 chapters)

  1. Front Matter

    Pages I-IX
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  2. Description, History, and Calorigenic Activity of Iodothyronines

    • Inder J. Chopra
    Pages 1-7

  3. Transport of Iodothyronines

    • Inder J. Chopra
    Pages 8-14

  4. Triiodothyronine: Molecular Structure and Biologic Function

    • Inder J. Chopra
    Pages 15-57

  5. Concentration of Triiodothyronines (T3 and Reverse T3) in Serum and Other Body Fluids

    • Inder J. Chopra
    Pages 58-94

  6. Kinetics of Peripheral Metabolism and Production Rates of T3s

    • Inder J. Chopra
    Pages 95-101

  7. Sources of T3s: Thyroidal Secretion Versus Extrathyroidal Metabolism of T4

    • Inder J. Chopra
    Pages 102-104

  8. Nature of the Processes of and Factors Influencing Production of T3s from T4

    • Inder J. Chopra
    Pages 105-113

  9. Routes of T3s Metabolism

    • Inder J. Chopra
    Pages 114-117

  10. Biologic Effects of Iodothyronines

    • Inder J. Chopra
    Pages 118-124

  11. Back Matter

    Pages 125-145
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Keywords

About this book

The physiology and metabolism of thyroid hormones were areas of intense research investigation during the 1970s. Radioimmunoassays were applied to study the concentration of iodothyronines in biologic fluids. These techniques proved to be highly sensitive, specific, and reproducible as well as rapid. The availability of specific radioimmunoassays led to the detection of several iodothyronines in human biologic fluids, e. g., reverse triiodothyronine (rT 3), diiodothyronines, monoiodothyronines, and acetic acid derivatives of thyroxine (T 4) and T 3, which were previously either unknown or briefly considered but forgotten in the 1950s. This monograph is intended for readers who desire an overview of thyroid hormone physiology as it was understood in 1979. It should be especially useful to trainees in endocrinology and individuals interested in potential research projects. The main focus has been on the studies conducted between 1969 and 1978, alt~lOugh other information has been reviewed to provide an overall working knowledge of the field. A list of over 500 references, although probably still incomplete, should lead a reader to at least a few important articles in each area relevant to thyroid hormone physiology.

Authors and Affiliations

  • Center for the Health Sciences, UCLA School of Medicine, Los Angeles, USA

    Inder J. Chopra

Bibliographic Information

  • Book Title: Triiodothyronines in Health and Disease

  • Authors: Inder J. Chopra

  • Series Title: Monographs on Endocrinology

  • DOI: https://doi.org/10.1007/978-3-642-81548-5

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin, Heidelberg 1981

  • Softcover ISBN: 978-3-642-81550-8Published: 15 December 2011

  • eBook ISBN: 978-3-642-81548-5Published: 06 December 2012

  • Series ISSN: 0077-1015

  • Edition Number: 1

  • Number of Pages: IX, 145

  • Number of Illustrations: 5 b/w illustrations

  • Topics: Endocrinology

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