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Current Topics in Microbiology and Immunology

DNA Vaccination/Genetic Vaccination

Editors: Koprowski, Hilary, Weiner, David B. (Eds.)

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  • - Enables the reader to understand how to apply important emerging technology to a new generation of vaccines and therapies

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  • ISBN 978-3-642-80475-5
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About this book

Genetic / DNA immunization represents a novel approach to vaccine and immune therapeutic development. The direct injec­ tion of nucleic acid expression cassettes into a living host results in a limited number of its cells becoming factories for production of the introduced gene products. This host-inappropriate gene expression has important immunological consequences, resulting in the specific immune activation of the host against the gene­ delivered antigen. The recent demonstration by a number of laboratories that the induced immune responses are functional in experimental models against both specific infectious diseases and cancers is likely to have dramatic consequences for the develop­ ment of a new generation of experimental vaccines and immune therapies. This technology has the potential to enable the pro­ duction of vaccines and immune-based therapies that are not only effective immunologically but are accessible to the entire world (rather than just to the most developed nations). Vaccine Development Vaccination against pathogenic microorganisms represents one of the most important advances in the history of medicine. Vaccines, including those against polio, measles, mumps, rubella, hepatitis A, hepatitis B, pertussis and other diseases, have dramatically improved and protected more human lives than any other avenue of modern medicine. The vaccine against smallpox, for example, has been so successful that it is now widely believed that this malicious killer, responsible for more deaths in the twentieth century than World Wars I and II combined, has been removed from the face of the earth.

Table of contents (11 chapters)

Table of contents (11 chapters)

Buy this book

eBook $109.00
price for USA in USD (gross)
  • ISBN 978-3-642-80475-5
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $139.99
price for USA in USD
  • ISBN 978-3-642-80477-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
DNA Vaccination/Genetic Vaccination
Editors
  • Hilary Koprowski
  • David B. Weiner
Series Title
Current Topics in Microbiology and Immunology
Series Volume
226
Copyright
1998
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-642-80475-5
DOI
10.1007/978-3-642-80475-5
Softcover ISBN
978-3-642-80477-9
Series ISSN
0070-217X
Edition Number
1
Number of Pages
XVIII, 198
Number of Illustrations
15 b/w illustrations, 2 illustrations in colour
Topics