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Current Topics in Microbiology and Immunology

Morphogenesis and Maturation of Retroviruses

Editors: Kräusslich, Hans-Georg (Ed.)

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About this book

Retroviruses arguably belong to the most fascinating of all viruses because of their unusual and highly efficient mode of replication involving reverse transcription and integration of the viral genome and a complex system of transcriptional and post­ transcriptional regulatory mechanisms. The importance of ret­ roviruses as human and animal pathogens has also enhanced scientific and medical interest in this diverse group of viruses and has spurred an intensive search for novel and improved antiviral agents. More recently, analysis of retroviral replication and in particular understanding the formation and composition of the virus particle has received additional attention because of the promise of retroviral vectors as vehicles for human somatic gene therapy. Many recent advances have been made in our understanding of the molecular mechanisms governing as­ sembly and release of infectious retrovirus particles. This book attempts to summarize these recent developments and to provide an overview of our current knowledge on retrovirus particle formation. The individual chapters of the book deal with specific steps in the pathway of retroviral morphogenesis and maturation, starting at the time when the components of the virus have been synthesized within the infected cell and ending once the infectious virion has been released from the cell. An introductory chapter provides a comparative description of the structure and morphology of various retroviruses.

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"The authors of this exemplary volume provide the most up-to-date review of their subject...The writing is precise and dynamic, supported by judiciously chosen illustrations...a wonderful contribution to a rapidly moving field. It will be enjoyed by students and teachers alike and will serve as a precious source of reference for even the most seasoned of researchers." Trends in Microbiology

Table of contents (10 chapters)

Table of contents (10 chapters)

Buy this book

eBook $119.00
price for USA in USD (gross)
  • ISBN 978-3-642-80145-7
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $159.00
price for USA in USD
  • ISBN 978-3-642-80147-1
  • Free shipping for individuals worldwide
  • Immediate ebook access, if available*, with your print order
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Morphogenesis and Maturation of Retroviruses
Editors
  • Hans-Georg Kräusslich
Series Title
Current Topics in Microbiology and Immunology
Series Volume
214
Copyright
1996
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-642-80145-7
DOI
10.1007/978-3-642-80145-7
Softcover ISBN
978-3-642-80147-1
Series ISSN
0070-217X
Edition Number
1
Number of Pages
XII, 344
Topics

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